How long does it take to have diarrhea after taking magnesium sulfate?

Magnesium sulfate is a common laxative drug, which has the function of emptying the stomach and intestines. There is no specific regulation on how long it will take to defecate after drinking magnesium sulfate. Some people defecate faster, and some people defecate slower. When drinking magnesium sulfate, you should understand some precautions, which can promote the effect of drug treatment. For example, if this treatment is to be carried out the next day, it is best to eat some liquid food that night.

1. Oral administration of magnesium sulfate solution of different concentrations may have different effects

1. Cathartic effect

Since it is not absorbed when taken orally, it forms a certain osmotic pressure in the intestine, which allows the intestine to retain a large amount of water, stimulating intestinal peristalsis and causing defecation.

Dissolve 5 to 20 grams of magnesium sulfate in 100 to 400 ml of warm water each time and take it orally once in the morning. The concentration should not be too high, 5% is best, otherwise defecation will be delayed.

2. Choleretic effect

Oral administration of high-concentration (33%) magnesium sulfate solution, or direct infusion into the duodenum using a catheter, can stimulate the duodenal mucosa, reflexively causing relaxation of the common bile duct sphincter and contraction of the gallbladder, thereby promoting gallbladder emptying and having a choleretic effect. Take 2-5g each time, 3 times a day, before meals or between meals. You can also take 33% solution, 10 ml each time.

It should be noted that if a large amount of solution with too high concentration is taken during catharsis, a large amount of water can be absorbed from the tissues and cause dehydration. Therefore, it is advisable to take it on an empty stomach in the early morning and drink plenty of water to accelerate the catharsis effect and prevent dehydration. This product is contraindicated for use as a laxative in patients with intestinal bleeding, pregnant women, patients with acute abdomen, and women during menstruation.

2. Intravenous injection of magnesium sulfate can be used as an anticonvulsant.

It is commonly used to treat pregnancy-induced hypertension, lower blood pressure, treat pre-eclampsia and eclampsia, and is also used to treat premature birth.

1. Treat moderate to severe pregnancy-induced hypertension, preeclampsia and eclampsia. The initial dose is 2.5-4 g, diluted with 20 ml of 25% glucose injection, and slowly injected intravenously within 5 minutes, followed by maintenance by intravenous drip of 1-2 g per hour. The total amount in 24 hours is 30g, which is monitored based on knee tendon reflex, respiratory rate and urine output.

2. Treat premature birth. The dosage and method are similar to those for the treatment of pregnancy-induced hypertension. The initial loading dose is 4 g; it is diluted with 20 ml of 25% glucose injection and slowly injected intravenously within 5 minutes. Later, 60 ml of 25% magnesium sulfate injection is added to 1000 ml of 5% glucose injection and intravenously dripped at a rate of 2 g per hour until 2 hours after uterine contractions stop. Oral adrenal receptor agonists are then taken to maintain the condition.

3. Magnesium sulfate for external use: reduces swelling and inflammation.

Since magnesium sulfate has the pharmacological effects of hypertonicity, detumescence and analgesia, it is used in clinical practice with satisfactory results.

Use gauze or absorbent cotton to fully soak it in 50% magnesium sulfate solution. You can apply hot or cold compress, depending on the symptoms of the affected area. If it is phlebitis, cold compress is mostly used. If the affected area is hardened and not red or the temperature is low, hot compress is often used. Generally, depending on the condition of the affected area, wet compresses are applied once or several times a day, with each compress lasting 30 minutes.