Low platelets with bleeding symptoms

Low platelet count is an important cause of bleeding. If you have low platelet count, you should go to the hospital for examination in time. There are many reasons for low platelet count in the human body. The most common one is blood disease. In addition, rheumatic immune disease and chemotherapy damage may also lead to thrombocytopenia, which will cause bleeding spots and even gum bleeding. More serious cases can cause internal bleeding.

Low platelets with bleeding symptoms

1. Skin bleeding, petechiae, purpura, and ecchymosis. 2. Bleeding gums Bleeding gums are common in normal people and those with dental diseases. Therefore, repeated gingival bleeding or difficulty in stopping bleeding often indicates bleeding diseases such as thrombocytopenia. 3. Blood blisters on oral mucosa. 4. Nosebleeds may occur occasionally in normal people, but nosebleeds combined with other bleeding symptoms often indicate bleeding diseases. 5. Joint bleeding, muscle and deep tissue hematoma. Simple thrombocytopenia causing joint and muscle bleeding is rare.

Causes of low platelet count 1. Decreased platelet production (1) Hereditary causes such as Fanconi anemia, congenital amegakaryocytic thrombocytopenia and May-Hegglin anomaly. (2) Acquired aplastic anemia, bone marrow infiltration (malignant tumor bone marrow metastasis, leukemia, myelofibrosis, tuberculosis), chemotherapy drugs, radiation, megakaryocytic aplasia, viral infection (measles, mumps), drugs that affect platelet production (such as alcohol), vitamin B12 and folic acid deficiency. 2. Increased platelet destruction caused by non-immune factors, such as thrombotic thrombocytopenic purpura, pregnancy, infection, hemangioma-thrombocytopenia syndrome, snake bites, acute respiratory distress syndrome, severe burns, etc. 3. Increased platelet destruction caused by immune factors: immune thrombocytopenic purpura, HIV infection, cyclical thrombocytopenia, drug-induced thrombocytopenia (heparin, quinine, quinidine, antipyretic analgesics, penicillin, cephalosporin antibiotics, rifampicin, furosemide, carbamazepine, sodium valproate, sulfonylurea hypoglycemic drugs and phenytoin sodium, etc.), and post-transfusion thrombocytopenia. 4. Abnormal platelet distribution, hypersplenism, and hypothermia. 5. Platelet loss bleeding, extracorporeal perfusion, and hemodialysis. 6. Other pseudothrombocytopenia.