If you feel itchy and scratch, and if bleeding spots appear or even like scraping, you should pay attention to it. There are many reasons for this phenomenon, such as low platelets and poor coagulation mechanism, blood disease, etc. It may also be caused by skin diseases. The most common one is artificial urticaria. Therefore, when this phenomenon occurs, you must go to the hospital for examination in time. Artificial urticaria is common in young people with allergic constitution. The cause of its occurrence is mostly due to the allergic reaction of the skin after external physical stimulation, which causes mast cells to release biologically active substances such as histamine, causing the skin capillaries to dilate, the permeability to increase, and the plasma and tissue fluid to penetrate into the dermis. People suffering from this skin scratching disease often feel itchy skin for no reason, but unlike the common urticaria, they do not have wheals all over the body. Instead, when the skin is scratched with nails or other blunt objects, erythematous wheals appear locally first, and then the wheals swell above the skin, and red halos appear at the edges of the erythematous wheals. Some patients with severe symptoms even have swollen lips after their lips are bitten by teeth. Various acute and chronic infectious factors can also cause this disease, including bacterial infection, viral infection and parasitic infection. Many medications and medical conditions can also cause hives. Mental factors and endocrine changes can also cause this disease. treat 1. Antihistamines The first generation of antihistamines are helpful for people whose sleep is affected by urticaria because of their drowsiness and sedation effects. Second-generation antihistamines not only have antagonistic effects, but also can act as inverse agonists and are often used in the treatment of chronic urticaria. The cause of chronic urticaria is difficult to find, the pathogenesis is complex, and antihistamines alone cannot control it. Depending on the condition, H2 receptor antagonists such as ranitidine can be added at the same time, or drugs that stabilize mast cell membranes such as tropanax notoginseng can be added and used in combination. To prevent drug resistance from long-term use of antihistamines, different types of drugs can be used when certain drugs are ineffective. For patients with controlled chronic urticaria, a gradual reduction in dosage or even discontinuation of medication is adopted to maintain remission. 2. Glucocorticoids 3. The use of immunosuppressants is generally not recommended for the treatment of urticaria due to the high incidence of side effects. Cyclosporine A can be used to treat autoimmune chronic urticaria. Intravenous immunoglobulin can be used for 5 consecutive days to treat severe autoimmune urticaria. Other immunosuppressants such as methotrexate and cellcept can also be used for autoimmune urticaria. |
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