Many people do not pay much attention to the problem of neurofibroma in normal times. Diseases like this are extremely sensitive in normal times. The treatment measure is generally surgical resection. Surgical resection will recover faster and can reach the lesion directly. However, in terms of treatment, it is also necessary to judge which treatment method will be more effective based on pathological changes. Treatment measures are not sensitive to radiation and should be surgically removed. The surgical approach can be through the anterior nasal cavity, through the lateral nasal incision, through the external nasal and ethmoid sinus approach, or through the Colu surgical resection, depending on the situation. The midface debulking surgery has the advantages of a wide field of view and no scars on the face after surgery. It is the best procedure for removing neurofibromas in the nasal cavity and sinus areas.Pathological changes: Meningioma has a complete capsule, is solitary, occasionally has edema or cystic changes, is generally benign, and rarely becomes malignant. Neurofibromas usually lack a capsule and can be solitary or multiple. If accompanied by subcutaneous nodules and skin pigmentation, it is multiple neurofibromas, also known as Von Recklinghausen's disease, which is prone to malignant transformation. In terms of pathological morphology, there are two types of tumor cell arrangement: ① Tumor cells are arranged in a spiral shape or parallel to each other, and the cells are arranged in a fence shape, which is Antoni Type A; ② Loose tissue structure, very similar to myxoma, cells have no fixed arrangement, size and shape are also uneven, there is often edema fluid between tumor cells, forming tiny cysts or vesicles, which is Antoni Type B. There is no significant gender difference in clinical manifestations , and most patients are young and middle-aged people. The disease grows slowly and may last for more than ten years. There are usually no symptoms in the early stages, but symptoms in the later stages depend on the location and size of the tumor, and may include nasal obstruction, minor nose bleeding, headache, and varying degrees of deformity of the nasal cavity or face. If there is Von Recklinghausen disease may cause intellectual disability. Overview Neurofibroma is a common benign tumor of the skin and subcutaneous tissue in clinical practice. It originates from the supporting connective tissue of the nerve sheath cells and mesenchymal tissue, and can occur in any part of the nerve trunk and nerve terminal. It can be single shot or multiple shot. However, multiple occurrences are the most common, and multiple occurrences are neuromas. 1. Clinical manifestations: Single neurofibroma protrudes from the skin surface and can be felt subcutaneously. It may be round, nodular or fusiform in shape. The texture can be both soft and hard, with most being softer. It is more common in adults and less common in children. The clinical manifestations and histopathology of solitary neurofibromas are the same as those of multiple neurofibromas. |
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