What happens if you have depression?

We all know that the cause of death of some celebrities is depression. Depression is also called depressive disorder, which is characterized by significant and persistent low mood.

The depression can range from melancholy to grief, low self-esteem, depression, and even pessimism and world-weariness. There may be suicidal attempts or behaviors; even stupor; some cases have obvious anxiety

and motor agitation; in severe cases, psychotic symptoms such as hallucinations and delusions may occur. So let’s take a look at what happens when you have depression!

1. Causes and related factors

To date, the cause of depression is not very clear, but it is certain that many biological, psychological and social environmental factors are involved in the pathogenesis of depression. biology

Factors mainly involve genetics, neurobiochemistry, neuroendocrine, and neural regeneration. The psychological susceptibility closely related to depression is pre-morbid personality traits, such as depressive temperament.

. Encountering stressful life events in adulthood is an important trigger for the onset of clinically significant depressive episodes. However, these factors do not work alone.

, emphasizing that the interaction between genetics and environmental or stress factors, as well as the timing of this interaction, have an important impact on the occurrence of depression.

Genetics

Studies have shown that the prevalence of depression in relatives of patients is 10 to 30 times higher than that in ordinary families, and the closer the blood relationship, the higher the prevalence: 14% for parents, children, brothers and sisters, 14% for uncles and 14% for uncles.

Aunts, uncles, grandparents, etc. account for 4.8%, and cousins ​​account for 3.6%. For monozygotic twins, it is 46%, and for dizygotic twins, it is 20%. [3] It can be seen that depression is closely related to genetics.

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2. Clinical manifestations

Depression can manifest as a single or repeated depressive episode. The following are the main manifestations of a depressive episode.

1. Depressed mood

The main manifestations are significant and persistent low mood, depression and pessimism. In mild cases, people feel depressed, unhappy, and have a loss of interest; in severe cases, people feel desperate, pessimistic, and feel that every day is a year.

Life is worse than death. The depressed mood of typical patients has a rhythmic change from heavier in the morning to lighter at night. On the basis of depressed mood, patients will have a lower self-evaluation, a sense of uselessness, hopelessness,

Feelings of helplessness and worthlessness are often accompanied by self-blame and guilt. In severe cases, delusions of guilt and hypochondriasis may occur, and some patients may experience hallucinations.

2. Slow thinking

The patient's thinking and association are slow, his reaction is unsuccessful, his train of thought is blocked, and he feels that his "brain is like a rusty machine" and "his brain is like covered with a layer of paste." Clinically,

There is a decrease in active speech, a noticeable slowing of speech speed, a deep voice, difficulty in conversation, and in severe cases, smooth communication is impossible.

3. Decreased willpower

The patient's volitional activity was significantly and persistently inhibited. Clinical manifestations include slow behavior, passive and lazy life, unwillingness to do things, unwillingness to interact with people around, often sitting alone, or

Stay in bed all day, live alone, alienate relatives and friends, and avoid socializing. In severe cases, they even neglect their physiological needs such as eating and drinking and personal hygiene, become unkempt and untidy, and even develop into

The patient does not speak, does not move, and does not eat, which is called "depressive stupor." However, a careful psychiatric examination shows that the patient still shows painful and depressed emotions. Patients with anxiety may fidget and grasp their fingers

, rubbing hands and feet, or pacing up and down, etc. Severe patients often have negative suicidal ideas or behaviors. Surveys show that 287,000 people die by suicide in my country every year, 63% of whom are mentally ill.

40% suffer from depression. [12] There are many celebrities who committed suicide due to depression, including Van Gogh, Hemingway, Sanmao, Leslie Cheung,[12] Xu Xing, Li Xiao, and Robin Williams.

, Qiao Renliang, etc.[3]. Negative and pessimistic thinking, self-blame and self-guilt, and lack of self-confidence can lead to despair, thinking that "ending one's life is a kind of relief" and "living in the world is useless".

This is the most dangerous symptom of depression and should be viewed with caution.