Complete autoimmune antibody test

A full set of autoimmune antibody tests is now a necessity, because these determine whether a person's body is healthy and whether the individual's body can recover. During the examination process, it is necessary to adjust according to the steps, and it may not be ruled out that it is caused by genetics, infection, drugs, environment and other factors, so special attention needs to be paid.

Symptoms ⑴ High titer autoantibodies can often be detected in the patient's serum. ⑵ Pathological changes related to immune response occur, and the lesion site is mainly chronic inflammation with infiltration of lymphocytes and plasma cells. ⑶ Most of the causes are unknown and may be related to genetics, infection, drugs and environmental factors. ⑷ The course of the disease is generally long, with repeated alternations of attacks and remissions. ⑸Generally, there are more women than men. ⑹Animal replication can be performed.

Classification Organ-specific autoimmune diseases Pathological damage and dysfunction of tissues and organs are limited to a certain organ targeted by antibodies or sensitized lymphocytes. The main ones include chronic lymphocytic thyroiditis, hyperthyroidism, insulin-dependent diabetes mellitus, myasthenia gravis, chronic ulcerative colitis, pernicious anemia with chronic atrophic gastritis, Goodpasture syndrome, pemphigus vulgaris, pemphigoid, primary biliary cirrhosis, multiple sclerosis, acute idiopathic polyneuritis, etc. The common ones will be described in each system disease respectively. Systemic autoimmune diseases are caused by the extensive deposition of antigen-antibody complexes in blood vessel walls, which lead to damage to multiple organs throughout the body. It is also commonly known as collagen disease or connective tissue disease. It is caused by immune damage leading to fibrinoid necrotizing inflammation of the vascular wall and interstitium and subsequent collagen fiber hyperplasia in multiple organs. In fact, whether from the perspective of ultrastructure or biochemical metabolism, most collagen fibers do not undergo primary changes.

Common autoimmune diseases include the following: ① Systemic lupus erythematosus. More common in middle-aged women. It is characterized by butterfly-shaped congestion rash on the face and cheekbones and extensive visceral lesions. The organs that are easily invaded include the heart, kidneys, lungs, liver, etc. "Typical" cases present an acute course with fever, joint pain, swollen lymph nodes, renal failure, etc., and can be fatal. But progress has been mostly slow. The main autoantigens of this disease are deoxyribonucleic acid, especially denatured deoxyribonucleic acid, in addition to nucleoproteins, blood cells, etc. Some drugs used to treat non-SLE can cause the production of antinuclear antibodies. The main ones among these drugs are hydralazine, procainamide, isoniazid, methyldopa, etc. Drug-induced systemic lupus erythematosus rarely causes renal damage, but other cases almost all have varying degrees of renal damage, which often leads to renal failure.

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