How does medroxyprogesterone tablets regulate menstruation?

How does medroxyprogesterone tablets regulate menstruation?

Medroxyprogesterone tablets are a relatively powerful progestin. Clinically, they mainly improve conception function by promoting the proliferation and secretion of the endometrium, and they also have the effect of preserving the fetus. In addition, appropriate use of medroxyprogesterone tablets can treat dysmenorrhea, functional amenorrhea and other diseases. It should be noted that you must maintain a happy mood during the medication period and cannot eat spicy and irritating foods.

1. Introduction of Medroxyprogesterone Tablets

Medroxyprogesterone tablets, also known as medroxyprogesterone acetate, medroxyprogesterone-Pharmacia Upjo, Provera, medroxyprogesterone, are strong progestins. Their main function is to promote the proliferation and secretion of the endometrium, complete the preparation for conception, and have a fetal preservation effect; they can also increase the viscosity of cervical mucus and inhibit ovulation. It is used for dysmenorrhea, functional amenorrhea, functional uterine bleeding, threatened abortion or habitual abortion, endometriosis, etc. Large doses can be used as a long-acting contraceptive injection.

2. Dosage and Usage

Breast cancer 500mg qd-bid. Hormone-sensitive or -dependent tumors such as endometrial cancer; palliative treatment of patients with various cancers; bone marrow protection during cancer chemotherapy 500mg~1g/day; functional amenorrhea: oral. 4–8 mg/day for 5–10 days

3. How does medroxyprogesterone tablets regulate menstruation?

Medroxyprogesterone acetate tablets are progestin drugs that act on the endometrium, promote the proliferation and secretion of the endometrium, inhibit the release of luteinizing hormone from the anterior pituitary through negative feedback on the hypothalamus, and inhibit the ovulation process of the ovary. The anticancer effect may be related to the anti-estrogen effect.

Medroxyprogesterone acetate tablets have a menstrual regulating effect. There are no symptoms before menstruation after taking them. The instructions indicate that menstruation usually occurs three to seven days after stopping the medication. During the treatment, you need to keep a calm mind, maintain a regular life, and avoid mental stress.

4. Adverse reactions of taking medroxyprogesterone tablets

Breast pain, galactorrhea, amenorrhea, cervical erosion or changes in cervical secretions may also produce effects similar to those of corticosteroids. Hand tremors, sweating and calf cramps at night. Obstructive jaundice.

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