Caseous necrosis

The term caseous necrosis is not often heard. This must be related to dietary issues. Because cheese often appears in food, today's industrial technology is well developed. We often process and produce food that satisfies everyone. But caseous necrosis means that cheese has no benefits to the human body. But what exactly is caseous necrosis?

Caseous necrosis is a type of coagulative necrosis. The necrotic tissue disintegrates completely, is soft, and slightly yellow in color, resembling dry cheese. Under the microscope, it appears as a structureless eosinophilic granular substance. There is no trace of the original tissue structure in the necrotic area, and even no nuclear debris is seen. This is a special type of more thorough necrosis: coagulative necrosis. In tuberculosis, because the lesions contain more lipids, the necrotic area is yellow and cheesy, which is called caseous necrosis.

Pathological characteristics: It occurs in patients with high allergic reactions. When a large number of tuberculosis bacteria invade, it causes coagulative necrosis, which is cheesy. After the cheese liquefies, it can be discharged through the bronchi. Caseous change is actually a characteristic manifestation of tuberculosis lesions. It is a type of coagulative tissue necrosis that is yellow in color, has increased lipids, and looks like cheese. Under microscopic examination, the cells first appear turbid and swollen, followed by fatty degeneration of the cytoplasm and dissolution and fragmentation of the cell nucleus until complete necrosis of the tissue. During the development of caseous changes, granulation tissue gradually appears around the lesions and finally forms a fibrous surround. The number of tuberculosis bacteria decreases as caseous necrosis begins; tuberculosis bacteria are rarely found in the caseous material. This lesion may not liquefy or absorb for a long time.

It is seen in tuberculosis. In the early stage of rheumatic lesions, it is fibrinoid necrosis of collagen fibers. Renal infarction is anemic infarction. Under the microscope, the anemic infarction foci show coagulative necrosis, and the tissue contour is still preserved. Hepatic amoebiasis is a type of tissue liquefaction necrosis caused by the secretion of large amounts of proteinase by Entamoeba histolytica; fat necrosis that occurs during acute pancreatitis is a special type of liquefaction necrosis.

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