Based on the characteristics of hypothyroidism and its mechanism of action on the body, people with hypothyroidism will lose weight. On the one hand, due to excessive thyroid secretion, the patient's excretion function will be greatly increased, resulting in a significant reduction in nutrient absorption, and the patient will eat more and excrete more. On the other hand, it will also make the patient's appetite and appetite worse, further forming a vicious cycle and causing the patient to lose weight. Hypothyroidism is actually an endocrine disease caused by a lack or insufficiency of thyroid hormone or a lack of response to it, which leads to a decrease in the body's metabolic activity. In life, we find that many patients with hyperthyroidism do not gain weight no matter how much they eat and their weight even decreases. So what is going on? Due to the effect of excessive thyroid hormones in the human body, intestinal peristalsis increases, which increases the frequency of bowel movements and even causes stubborn diarrhea, which is called hyperthyroid diarrhea. The patient's stool is generally mushy and contains more undigested food, without abdominal pain, prolapse and tenesmus, no white blood cells and pus cells in microscopic examination, no pathogenic bacteria growth in stool culture, and antibiotic treatment is ineffective. The condition improves as the hyperthyroidism is relieved. Sometimes it presents as steatorrhea due to fat malabsorption. Some patients with hypothyroidism suffer from nutritional disorders and the direct effects of thyroid hormones. The liver may be slightly enlarged, few people have obvious liver damage, and a few may have abnormal liver function. Therefore, hypothyroidism can also cause weight loss. Hypothyroidism is a clinical syndrome caused by insufficient synthesis, secretion, or biological effect of thyroid hormone. This disease is usually caused by lesions in the thyroid gland itself, that is, primary hypothyroidism. The decrease in thyroid hormone secretion due to insufficient secretion of thyroid stimulating hormone (TSH) by the pituitary gland or insufficient secretion of thyrotropin-releasing hormone (TRH) by the hypothalamus is called secondary hypothyroidism or central hypothyroidism. Among them, hypothyroidism caused by TRH deficiency due to hypothalamic lesions is called tertiary hypothyroidism. Clinical manifestations include mental disorders, cerebellar ataxia, etc. It is more common in people aged 40 to 60 years old, and is more common in women, about 5 times that of men. |
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