Is male congenital genital malformation hereditary?

Various congenital problems often occur, such as congenital genital malformations in men, genital hypoplasia, short genitals, undeveloped genitals, etc. These will cause the patient to lose his normal physical state and may even affect the future reproductive function. Whether it is hereditary or not also needs to be examined to know.

Disease Introduction/Male Genital Deformity

There are many types of male genital malformations. Some congenital malformations only affect fertility, such as simple absence of the vas deferens; while others may also affect sexual function. Some deformities may not seem serious, such as phimosis, but they can also have serious consequences if not handled properly.

Causes/Male genital malformations

This disease is a congenital disease. In cases where there are abnormalities in fetal development, most of them are not discovered until after the fetus is born.

Presentation and Diagnosis/Male Genital Anomalies

1. Testicular deformity

Abnormal quantity:

(1) Atesticular disease. Rarely, probably due to some reasons during embryonic development causing incomplete testicular differentiation, resulting in testicular atrophy and degeneration. However, because some interstitial cells still exist, the patient can have male external genitalia and appearance. It should be differentiated from bilateral cryptorchidism. The disease is characterized by increased luteinizing hormone (LH) in the blood, and the plasma testosterone level does not increase after the administration of chorionic gonadotropin. Androgens should be given regularly after puberty. Otherwise, eunuch syndrome may occur, and testicular transplantation can be performed using testicles from siblings or allogeneic testicles. This disease is often accompanied by the absence of vas deferens and epididymis.

(2) Single testicle. Most of them do not require special treatment. The purpose of surgical examination is to find hidden testicles that may exist in the abdominal cavity to prevent them from becoming cancerous.

(3) Polytestis. Refers to the presence of 3 or more testicles. Size anomaly:

(4) Testicles that are smaller than normal due to incomplete development are usually not an isolated symptom.

(5) The testicles become enlarged due to hyperplasia, such as testicular teratoma.

(6) Congenital atrophy. Abnormal location:

(7) Testicular fusion. It refers to the fusion of both testicles in the abdominal cavity or scrotum, which can be easily mistaken for cryptorchidism or monoorchia. Often accompanied by renal malformations.

(8) Cryptorchidism

(9) Ectopic testis.

(10) Abnormal attachment of the testicles and epididymis may hinder the passage of sperm and cause infertility. If the two are not connected well, testicular torsion can easily occur, and even tissue necrosis can occur due to incomplete blood supply.

2. Vas deferens malformation

It can be divided into many situations, such as congenital absence, communication with the ureter, and duplicated vas deferens.

If there is no other malformation and it is just a simple absence of the vas deferens, the patient's sexual desire and sexual function are normal, and the only symptom is infertility. The clinical manifestation is azoospermia, but the serum hormone levels are normal, which can be confirmed by testicular biopsy. If possible, surgical treatment to anastomose the vas deferens stump to the epididymis