What to do if you have premature ovarian failure at the age of 29

For women aged 29, they are in a very awkward period of age. Because women's body functions will gradually decline after the age of 25, women in this period must pay special attention to taking care of their bodies. As an important reproductive organ in women, the role of the ovaries is self-evident. So what should a 29-year-old woman do when she finds that she has premature ovarian failure?

Many people blindly believe that the disease can be cured by supplementing hormones, which is wrong. First, estrogen supplementation cannot cure the root cause, it can only improve symptoms, not the function of the ovaries; second, long-term and large-scale estrogen supplementation will not only bring certain side effects to the body, but also put the ovaries in a "dependent" state. When the drug is stopped, the estrogen deficiency may become worse, and may even lead to worse ovarian function. Traditional Chinese medicine treatment: Traditional Chinese medicine believes that the pathogenesis of premature ovarian failure is related to insufficient kidney water and hyperactivity of liver yang. Insufficient kidney water often leads to a deficiency of Yin essence, which can lead to a series of Yin deficiency symptoms, such as hot face, irritability, restless sleep, tinnitus, etc. Yin deficiency often leads to Yang hyperactivity. The inability of kidney water to nourish liver wood will naturally lead to liver Yang hyperactivity. These pathogenesis also laid the foundation for TCM treatment of "seeking the root cause of the disease".

Patients with premature ovarian failure can recover their fertility function after systemic treatment once ovulation occurs. The following methods are currently used:

⑴ In the artificial cycle, take 0.25-1 mg/day of ethoprogesterone from the 6th day of the normal cycle for 20 consecutive days, and take 10 mg/day of medroxyprogesterone from the 16th to the 25th day of the cycle, or inject 20 mg of progesterone intramuscularly every other day from the 17th day of the cycle for 5 consecutive times.

⑵Gonadotropin : The author believes that patients with premature ovarian failure may have low biological activity of FSH and LH, and use large amounts of gonadotropin for treatment to achieve the purpose of follicular development, ovulation, and pregnancy. There are also reports of patients being treated with chlorpheniramine.

⑶ For patients with immunosuppressive agents, especially those with combined adrenal insufficiency or premature aging, in addition to the above artificial cycles, cortisol such as dexamethasone can be added for treatment, and there have been successful reports.

⑷ Treatment combining traditional Chinese and Western medicine: It has been reported that patients with hypergonadotropin-induced amenorrhea often suffer from renal yin failure and liver and kidney fire inflammation, and should be treated with the method of nourishing yin and reducing fire, and tonifying the kidney and activating blood circulation. Take one dose of medicinal Zhimu, Phellodendron, Tortoise Shell, Turtle Shell, Ligustrum Lucidum, Epimedium, Peach Kernel, Rehmannia Glutinosa, Red Peony Root, and Angelica Sinensis decocted in water daily. Use ethopropanol 0.5-1 mg/day for 20 days, and then continue taking the medicine after menstruation comes.

Chinese Medicine

Traditional Chinese Medicine's green dialectical therapy uses medication in stages according to the different changes in the menstrual cycle, endometrium, and ovaries. It combines traditional Chinese medicine's syndrome differentiation with Western medicine's disease differentiation, and provides personalized treatment mainly with traditional Chinese medicine. It not only takes into account the cyclical changes of the ovaries during the menstrual cycle, but also conforms to the changes of yin and yang in the body, maintains the characteristics of traditional Chinese medicine's inherent dialectical diagnosis and treatment and overall adjustment, and achieves outstanding therapeutic effects.

Three characteristics of TCM green dialectical therapy

1. Comprehensive conditioning and enhancing immunity: Using traditional Chinese medicine for comprehensive conditioning, by regulating qi and blood, removing blood stasis and dispersing knots, and replenishing Chong and Ren meridians, the functions of various female organs are regulated, the secretion levels of estrogen and progesterone tend to be balanced, and the whole body immunity is enhanced;

2. Treat the disease from the inside out by using Chinese medicine’s characteristic of curing the root cause. For acne, chloasma, irregular menstruation, dysmenorrhea, amenorrhea and other lesions caused by premature ovarian failure, detoxification, blood circulation, blood stasis removal and skin beautification treatment are carried out;

3. TCM guidance and flexible treatment: guided by modern Chinese and Western medicine theories, the patients’ lifestyle, diet, and spirit are regulated to help them maintain a good state of thought, consciousness, and behavior.

Treatment options

●● For contemporary white-collar women, there is a general phenomenon of delaying marriage and childbearing. However, some women may experience ovarian dysfunction before the age of 40 or even at the age of 35. This phenomenon is called premature ovarian failure. Premature ovarian failure is often accompanied by autoimmune diseases, which is not uncommon nowadays.

●● In addition to amenorrhea, only a few people with premature ovarian failure experience symptoms similar to menopausal syndrome. However, young women may experience uterine atrophy, decreased vaginal secretions, sexual intercourse pain, and even osteoporosis due to long-term low estrogen status, so estrogen supplementation should be carried out in a timely manner. It is currently believed that premature ovarian failure is not necessarily irreversible, and active treatment should still be given, especially for patients who desire to have children.

●● Artificial cycle treatment method. Cyclic supplementation of estrogen and progesterone can avoid epithelial atrophy and calcium loss in the reproductive organs, and can protect the cardiovascular system and prevent changes in lipid metabolism. Oral estrogen can be started at any time, such as 0.5-1 mg of diethylstilbestrol, once a night for 22 consecutive days. Start supplementing progesterone on the 11th day of medication, such as taking 8-10 mg of medroxyprogesterone acetate (progesterone acetate) orally once a night for 10 consecutive days. If you use progesterone injection, start taking estrogen on the 16th day and inject 10 mg intramuscularly daily for 5 consecutive injections. If you take 5 micrograms of ethinyl estradiol, you only need to take it once a night for 20 to 22 days, and then add progestin.

●● Method of inducing follicle development. After a period of artificial cycle treatment, small doses of estrogen can be used alone, such as 0.5 mg or 0.25 mg of diethylstilbestrol (12.5 micrograms of ethinyl estradiol), once a night for 3 weeks and then stop for 1 week. Regardless of whether there is withdrawal bleeding or not, the second cycle of treatment will be started, and 3 cycles constitute a course of treatment.

●● Immunosuppressant therapy. People with adrenal insufficiency can be treated with cortisol.

●● Traditional Chinese medicine treatment or a combination of Chinese and Western medicine treatment. This treatment method often has good therapeutic effects. The more commonly used method of traditional Chinese medicine is to use yin-nourishing and heat-reducing, kidney-tonifying and blood-activating drugs in combination with estrogen, in the hope that the ovaries will gradually restore function. .