Causes of low alkaline phosphatase

Various organs in our body contain different enzyme components, and alkaline phosphatase is one of them. It is contained in many organs, such as the liver, kidneys, and placenta, and it is mainly present in the liver. It is for this reason that if there is an abnormality in alkaline phosphatase, it means that your liver may be damaged.

The most common clinical condition is high alkaline phosphatase. Many liver diseases can cause high alkaline phosphatase. Although low alkaline phosphatase is relatively rare, people still cannot ignore its harm. We need to know the reasons for low alkaline phosphatase.

Normal values ​​of alkaline phosphatase

When it comes to the normal value of alkaline phosphatase, it is different for adults and children. The alkaline phosphatase content of adults is often lower than that of children. The normal range of alkaline phosphatase for adults is 32-92 international units, and the normal range of alkaline phosphatase for children is 36-213 international units. The main reason for this difference is that children produce extra alkaline phosphatase during their growth and development.

Causes of low alkaline phosphatase

1. Common in patients with severe chronic nephritis and thyroid dysfunction.

2. Malnutrition and cretinism

3. Vitamin C deficiency: scurvy, celiac disease, cachexia

4. Hereditary hypophosphatasia

Causes of elevated alkaline phosphatase

High alkaline phosphatase is common in various liver diseases, bone diseases, etc. For example, alkaline phosphatase will increase when rickets and bone tumors occur. Some kidney diseases and leukemias are accompanied by high alkaline phosphatase. Of course, not all high alkaline phosphatases are caused by diseases. For example, children's rapid growth and women's pregnancy will exceed the normal range. So when alkaline phosphatase is high, don't panic. It is better to check first.

After knowing the reasons for low alkaline phosphatase, I believe you must have realized that the factors that lead to low alkaline phosphatase are generally pathological factors. This is also the main reason why people cannot ignore it. If you are diagnosed with low alkaline phosphatase, please check the above diseases in time.