Causes of gout

There are many symptoms of gout. In fact, we know that no matter what type of disease it is, it has unique symptoms and causes. The cause of disease is the fuse that causes the disease. Only by knowing this fuse clearly can we research ways to treat these diseases. Once a disease occurs, it will have some impact on the patient's life. Generally, before studying and treating a disease, it is necessary to have a clear understanding of the other components of the disease.

The occurrence of disease must have a cause and cannot happen naturally. The only natural thing in life is the phenomenon of birth and aging. As we age, our body's structure and ability to resist infection from external pathogens will decline. Therefore, we still need to pay more attention to diet to increase immunity. So what is the cause of gout?

Gout is a metabolic disease caused by abnormal purine metabolism leading to increased uric acid synthesis. Abnormal renal function can also cause an increase in uric acid levels due to a decrease in the kidney's uric acid clearance rate. Plasma saturation with uric acid results in the deposition of monosodium urate crystals in the relatively avascular tissues surrounding distal joints. The appearance of these crystals can lead to acute inflammatory synovitis in one or more joints. Gout is more common in men, and the big toe is the most commonly affected area, with 50% to 70% of initial onset occurring here. 90% of gout patients will have involvement of the first metatarsophalangeal joint at some time in their lifetime. Other areas of the foot that may be affected are the dorsum of the foot, the heel, and the ankle. In addition to affecting the joints, uric acid crystals can also be deposited under the skin in areas called tophi.

During the acute attack of stroke, symptoms should be relieved by resting, raising the affected limb, wearing shoes with hard soles, and open-toed postoperative shoes. Medical treatment includes high-dose nonsteroidal anti-inflammatory drugs or colchicine. When chronic gouty nodules are present, the symptomatic areas can be cleaned or the deposits removed. Severe joint destruction due to gout and pyrophosphate arthropathy is treated the same as degenerative arthritis of the first metatarsophalangeal joint or hallux rigidus. Joint debridement, implant arthroplasty and arthrodesis are all reasonable options for treating moderate to severe joint destruction.

The above describes the causes of gout, which are also known as the etiology. Generally, there are causes for diseases, and these causes are also for us to better study the conditions for treating these diseases. However, as long as the cause and symptoms of the disease are clearly understood, treatment can be quickly sought, which can improve the patient's condition.