What is the knowledge about vaccination?

Vaccination is an external intervention method for children to enhance their immunity and get rid of epidemic diseases at a young age. However, why does vaccination knowledge cause fever? This means that children will have a fever after vaccination. Why is this? Is it due to allergies or some other adverse reaction? If you are a parent who is confused about this, you might as well learn about it.

What is the knowledge about vaccination? Fever is the most common reaction after vaccination, and is mainly caused by pyrogens. Pyrogen is a high-molecular-weight complex of phospholipids, polysaccharides and proteins, mainly composed of lipopolysaccharides, among which lipid A is toxic. Pyrogens are mainly present in the cell walls of Gram-negative bacteria. They can only be released when the bacteria autolyze or are artificially lysed, so they are called endotoxins. It can directly act on the body temperature regulation center, causing disorder in the body temperature regulation function and causing fever; it can also act on the body's reticuloendothelial cells, epithelial cells, and especially neutrophils, causing them to release endogenous pyrogens, and then change the functional state of the body temperature center, causing heat production and heat dissipation to lose their relative balance, that is, heat production increases and heat dissipation decreases, causing fever. In addition to pyrogens, vaccines, as foreign proteins, and the inflammatory response after vaccination can also cause fever. Live vaccination is equivalent to a mild artificial natural infection, and a small number of people will also have a fever reaction.

The essence of fever is an adaptive defense response of the body. When fever reaches a certain level, due to enhanced metabolism and an increase in white blood cells, the functions of the reticuloendothelial system, including phagocytosis, antibody formation and the detoxification function of the liver, are correspondingly enhanced, thereby helping to eliminate pathogens and being beneficial to the human body. However, if the fever lasts too long or is too high, it will cause dysfunction of various systems, such as poor digestion and absorption, excessive consumption of nutrients in the body, reduced body resistance and even exhaustion. Excessive body temperature can cause convulsions and coma, and even endanger life. These adverse aspects should be taken seriously.

What is the knowledge about vaccination? Although this reaction is common after vaccination. However, if the child's body temperature is too high, or the high body temperature persists for a considerable period of time and remains high. Parents of children should realize that this is not a normal phenomenon and should take their children to a regular hospital for treatment to avoid delaying the disease.