What is the most effective treatment for tension headaches?

When facing the treatment issue of tension headaches, you must consult a professional doctor, especially since there are many kinds of medications to use, so you must choose scientifically to reduce some adverse side effects and harm. Naproxen and ketoprofen are both treatment drugs.

(1) Ketoprofen (ketoprofen) :

It belongs to the NSAID class and is used for tension-type headaches as well as muscle and joint pain. The analgesia is temporary and its function is to inhibit the synthesis of prostaglandins, increase intracellular cAMP, and improve platelet function. The oral dose is 12.5 to 25 mg/time. The toxic and side effects include stomach discomfort, nausea, diarrhea, palpitations, sweating, drowsiness and skin itching.

(2) Naproxen:

Belongs to the NSAID class. It has analgesic and anti-inflammatory effects by inhibiting the synthesis of dinoprost (prostaglandin). The oral dose is 100-200 mg/time, usually 2-3 times/day. The side effects are nausea, stomach upset, fatigue, dizziness, weakness and drowsiness. It is forbidden to use in pregnant and lactating women.

(3) Proquazone:

Belongs to the NSAID class. For acute tension-type headaches. Its pharmacological action involves inhibition of the prostaglandin system, and dinoprost (prostaglandins) is considered to be the physiological mediator of headache. It can also inhibit platelet aggregation, inhibit 5-HT release, reduce capillary permeability and inhibit bradykinin. The oral dose is 75-150 mg/time, and the side effects include nausea, vomiting, drowsiness, etc.

(4) Amitriptyline:

It is a tricyclic antidepressant and is an early drug used for chronic tension-type headache accompanied by depressive symptoms. This drug is both a norepinephrine reuptake inhibitor and a 5-hydroxytryptamine reuptake inhibitor. The latter was previously believed to be the main analgesic pathway of the drug, but recent studies have shown that the two effects have no difference in analgesic effect, and that the improvement in headache is indirect and mediated by the antidepressant effect. The oral dose is initially 75 mg/d and then gradually increased to 150 mg/d, taken in divided doses. The side effects include nausea, vomiting, fatigue, drowsiness, dizziness and insomnia. It is not recommended for patients with severe heart disease or glaucoma.