Lymphoma symptoms, these six are the most common!

At present, lymphoma is a relatively common tumor disease with obvious symptoms, such as swollen lymph nodes, low immune function, invasion of the liver and spleen, damage to extranodal organs, anemia, skin lesions, etc.

1. Swollen lymph nodes : Most patients present with painless cervical lymph node enlargement in the early stages, and other parts of the body are subsequently discovered. The lymph nodes can range in size from soybeans to dates, and are of medium hardness, tough, uniform, and plump. Generally, there is no adhesion to the skin, and it does not fuse with each other in the early and middle stages and is movable. In the later stages, the lymph nodes may grow very large or fuse together into large masses with a diameter of more than 20 cm. Some patients have multiple swollen lymph nodes from the onset of the disease, making it difficult to determine where the initial site is.

2. Impaired immune function : Since HD patients, especially those in the advanced stage, have low immune status, they may develop central nervous system infections such as Cryptococcus neoformans; hematogenous purulent meningitis or brain abscess may also occur. Malignant lymphoma invading the brain parenchyma may be accompanied by cerebral hemorrhage.

3. Liver and spleen : Primary hepatic malignant lymphoma is rare, with only a few case reports in the literature. Secondary invasion of the liver is not uncommon. The prognosis of patients with liver involvement is poor, even worse than that of patients with systemic symptoms.

4. Extranodal organs: It usually occurs in NHL. In rare cases, HD may also have extranodal organs such as bones, pharyngeal lymphatic rings, skin, digestive tract, central nervous system, etc.

5. Anemia: About 10% to 20% of patients with malignant lymphoma have anemia when they seek medical treatment, and it may even occur several months before lymph node enlargement. Anemia is more common in patients with advanced disease. Progressive anemia and increased erythrocyte sedimentation rate are important clinical indicators for determining whether malignant lymphoma develops or not.

6. Skin lesions : Patients with malignant lymphoma may have a series of non-specific skin manifestations, with an incidence of approximately 13% to 53%. Common ones are pellagra-like papules, herpes zoster, systemic dermatitis herpetiformis, pigmentation, ichthyosis and exfoliative dermatitis. Urticaria, erythema nodosum, dermatomyositis, pigmented urticaria, etc. may also occur. Scratching and skin infections caused by itchy skin are more common. Patients with advanced malignant lymphoma have low immunity and skin infections often cause long-term ulceration and exudation, resulting in systemic scattered skin thickening and desquamation.

Every year, people in the world lose their lives to lymphoma, so everyone should pay attention to this disease. If you find that you have early symptoms of lymphoma, you should go to the hospital for treatment immediately, because early lymphoma is the easiest to treat and the easiest to cure.