What are the effects and functions of Siegesbeckia sibiricum?

Many people may not know about Siegesbeckia, but in fact its medicinal value is very high. It can help us effectively dilate blood vessels and lower blood pressure. It can also improve microcirculation and fight against pathogens such as Staphylococcus aureus.

1. Immunosuppression

Siegesbeckia has an inhibitory effect on both cellular and humoral immunity. Intraperitoneal injection of Siegesbeckia scoparia decoction into mice for 7 consecutive days can reduce the lymphocyte count, Ea and Et rosette formation rates, antibody serum titers, and the positive rate of intracellular DNA and RNA acridine orange fluorescence staining.

It also has an inhibitory effect on nonspecific immune function. The water decoction of Siegesbeckia serrata inhibits the phagocytic function of peritoneal macrophages in mice, reduces the activity of serum lysozyme, and reduces the weight of the thymus and spleen.

(ii) Anti-inflammatory

Gavage of the decoction of Xitong Pills to rats can significantly inhibit the swelling of formaldehyde-induced and egg white-induced arthritis. Adenosine glycolic acid, adenosine glycolic acid, and adenosine diacid all have anti-inflammatory effects. Gavage of diterpenoid compounds from the stem of Semen Armeniacae Adenophorae to rats can significantly inhibit plantar swelling.

(III) Vascular dilation and blood pressure reduction

This product has the effect of dilating blood vessels. The extract can significantly dilate the blood vessels in rabbit ears with preserved nerves and block the vasoconstriction reaction caused by nerve stimulation.

This product has a blood pressure lowering effect. When the decoction is injected intraperitoneally into cats, blood pressure gradually decreases after 10 minutes and can last for 1.5 hours. Diterpenoid compounds such as adenosine glycolic acid are its active ingredients.

(IV) Improving microcirculation and anti-thrombotic

Siegesbeckia solution has a promoting effect on the blood flow recovery of mesenteric microcirculation in mice, which is comparable to that of Salvia miltiorrhiza injection. Intravenous injection in rabbits can significantly inhibit thrombosis. Significantly reduce the wet weight of thrombus.

(V) Others

1. Darutoside has a significant anti-early pregnancy effect on rats.

2. Antibacterial and antimalarial. In in vitro tests, the herb has inhibitory effects on Candida albicans and Staphylococcus aureus. The decoction has a significant inhibitory effect on mouse Plasmodium.