How long does it take for cephalosporin to be metabolized in the body?

Cephalosporin is a common drug in real life. Taking or injecting cephalosporin can effectively treat inflammation in the body and inflammation in the body's organs. Cephalosporin is an antibiotic drug. Generally, the metabolism time after taking or injecting it will vary depending on the different physical conditions of the human body. Generally, it will be metabolized within 6-7 days.

How long does it take for cephalosporin to be metabolized in the body?

Generally, you can drink alcohol about a week after taking cephalosporins to avoid a double-flow reaction. Drink plenty of water and get enough rest.

Absorption of various drugs

Select antibiotics based on the absorption, distribution and excretion characteristics of various drugs. Antimicrobial drugs have absorption, distribution and excretion processes in the body, and some drugs can be metabolized in the body.

(1) Absorption process: The degree and rate of absorption of different antibacterial drugs are also different. Generally, the drug is absorbed into the blood 1 to 2 hours after oral administration and 0.5 to 1 hour after intramuscular injection, and the blood drug concentration reaches a peak. Antibiotics that are completely absorbed orally include chloramphenicol, chloramphenicol, clindamycin, ceftriaxone, amoxicillin, rifampicin, doxycycline, etc. After oral administration, 80% to 90% of the administered dose can generally be absorbed; penicillins are easily destroyed by gastric acid, and oral ampicillin and oxacillin can be destroyed by gastric acid.

After oral administration, only 30% to 40% of the administered dose is absorbed; aminoglycosides, most types of cephalosporins, polymyxins, vancomycin, and amphotericin B are all absorbed very little after oral administration, about 0.5% to 3.0% of the administered dose. Due to the differences in the absorption process of various drugs, when treating mild and moderate infections, antibiotics that the pathogens are sensitive to and are easily absorbed orally can be selected. For more serious infections, intravenous administration is appropriate to avoid the effects of various factors on their absorption during oral or intramuscular injection.

(2) Distribution: Antimicrobial drugs that enter the blood circulation in a free state have small molecules and can be rapidly distributed to various tissues and body fluids to reach the site of infection. Different antimicrobial drugs have different distribution characteristics. Clindamycin, lincomycin, fosfomycin, and certain varieties of fluoroquinolones can reach higher concentrations in bone tissue.

The above-mentioned antimicrobial drugs with high bone concentrations can be used to treat bone infections. The concentrations of antimicrobial drugs in prostate tissue are mostly low, but erythromycin, sulfamethoxazole, trimethoprim, tetracycline,

Fluoroquinolones can reach effective concentrations in prostatic fluid and prostate tissue. The concentration of drugs in cerebrospinal fluid can reach lower than that in blood, but some drugs have good penetration of the blood-brain barrier. In case of meningeal inflammation, the concentration of drugs in cerebrospinal fluid can reach 50-100% of the blood concentration, such as chloramphenicol, sulfadiazine, penicillin, ampicillin, isohydrazine, 5-fluorocytosine, metronidazole, etc.; benzylpenicillin, ceftriaxone, erythromycin, polymyxin, marvan