What is the cause of male urethral ulcer?

In daily life, ulcers at the male urethral opening are a relatively common urinary system disease. Ulcers at the urethral opening are not only prone to diseases of the reproductive organs, but also prone to local infections, which have a great impact on physical health. There are many reasons for ulcers at the male urethral opening. Generally, this is caused by urethral infection and requires timely treatment.

What is the cause of male urethral ulcer?

This situation is called balanitis, which is usually caused by local uncleanliness and infection.

The main causes of urinary tract infections are as follows:

Obstruction and reflux

Both urinary tract obstruction and reflux can cause abnormal changes in urodynamics, resulting in poor urine drainage and retention in the urinary tract, which can easily lead to infection. There are two causes of obstruction and reflux:

1) Mechanical obstruction, such as congenital malformations, stones, foreign bodies, scar contracture caused by chronic inflammation, and prostate hypertrophy.

2) Neurological functional obstruction and reflux, such as neurogenic bladder, congenital anatomical defects, megaureter, ureterovesical reflux, etc.

Both urinary tract obstruction and reflux can hinder urine drainage and cause localized urine retention. Since urine is a good environment for bacterial growth, it is prone to infection. According to statistics, the incidence of obstructive urinary tract infection is more than 10 times higher than that of non-obstructive infection, and the incidence of lower urinary tract obstruction is 2 times higher than that of upper urinary tract obstruction. In cases of recurrent urinary tract infection, it is necessary to check for the presence of urinary tract obstruction and reflux. These factors must be eliminated, otherwise it will be difficult to cure.

Pregnancy

During pregnancy, changes in the body's endocrine system and compression of the lower ureter by the uterus can cause poor urine drainage. At 10 weeks of pregnancy, dilatation of the renal pelvis and ureter can be seen from intravenous pyelography, especially on the right side. It has been measured that the urine volume in the renal pelvis and ureter of a normal person is 6 to 15 ml, which can reach 20 to 60 ml during pregnancy. This retention and delayed excretion of urine can easily lead to infection.

During prenatal examinations, it is found that 2% to 13% of pregnant women have asymptomatic bacteriuria. If left untreated, more than 25% to 40% of patients will develop symptomatic urinary tract infection (acute pyelonephritis). Urinary tract infection can occur at various stages during pregnancy, so bacterial culture is required multiple times. As for the issue of urinary tract infection and renal function damage, the urine concentration test can be used as an exploration. Pregnant women with urinary tract infection will have a decreased urine concentration ability. After treatment, the urine concentrating function can return to normal after the bacteria in the urine are eliminated. It is currently believed that changes in urine concentrating function are caused by renal papillary inflammation or reduced blood flow. In animal experiments, a large number of bacteria entered the kidneys without causing renal function loss. However, if bacteria invaded the renal papillae, renal function impairment occurred. It has been shown that acute pyelonephritis occurring during pregnancy often invades the renal papillae and results in a decrease in endogenous creatinine clearance.

Diabetes Problems

It is well known that diabetic patients are prone to infection due to a series of metabolic disorders and changes in immune function, and once the infection occurs, it is more difficult to control. It is reported that the incidence of urinary tract infection in diabetic patients is 5 times higher than that in normal people. At the same time, it was found that 20% of female diabetic patients suffered from asymptomatic bacteriuria. Therefore, it is unanimously advocated that diabetic patients should avoid unnecessary urinary tract instrument examinations; if examination is necessary, blood sugar should be controlled first and then the examination should be performed, and bacterial growth in the urine should be eliminated as much as possible.

Kidney disease problems, repeated urinary tract infections can easily cause urethral obstruction, further leading to the formation of obstructive nephropathy and aggravating renal damage. If not actively treated, it will lead to a sharp decline in renal function. In severe cases, it can cause acute renal failure, which can sometimes be irreversible.

Congenital malformations

There are many congenital malformations that often occur in the urinary system, such as horseshoe kidney, ectopic kidney, renal malrotation, stenosis of the renal-ureteral junction, bilateral ureter and bilateral renal pelvis malformation, ectopic ureteral opening, bladder exstrophy, etc. These lesions can often cause urinary tract obstruction and lead to infection.