How to prevent recurrence of purpuric nephritis

Purpura nephritis is an inflammatory reaction of the kidneys caused by Henoch-Schonlein purpura and is related to the body's own immunity. Purpura nephritis generally occurs after allergic purpura. Its cause may be allergic reaction caused by infection with bacteria, viruses and parasites, or allergic reaction caused by pollen, eggs, fish and meat. The recurrence rate of purpura nephritis is relatively high. Next, let’s take a closer look at how to treat purpura nephritis and prevent the recurrence of purpura nephritis?

Treatment

1. Western medicine treatment

The treatment plan is determined according to the pathological type of renal puncture. Hormones and immunosuppressants can be given, but attention should be paid to the side effects of hormones and immunosuppressants. The treatment effect is poor in some patients, which may lead to chronic renal failure.

2. Traditional Chinese Medicine Treatment

(1) Dispelling wind and clearing heat, detoxifying and activating blood circulation: Applicable to wind-heat, toxicity and blood stasis syndrome. The prescription uses Yinqiao Powder with added ingredients (honeysuckle flower, forsythia, loblolly leaf, reed root, platycodon, scrophularia, rehmannia root, imperata root, thistle, safflower, madder cordifolia).

(2) Clearing heat and dispersing blood stasis, cooling blood and stopping bleeding: Applicable to the syndrome of blood heat and blood stasis. The prescription is Rhinoceros Horn (replaced by water buffalo horn) and Rehmannia Decoction with added ingredients (water buffalo horn, Lithospermum officinale, red peony root, moutan bark, raw rehmannia, small thistle, Sophora japonica flower, Poria cocos, and Imperata root).

(3) Clearing away dampness and heat, detoxifying and activating blood circulation: Applicable to the syndrome of dampness, toxicity and blood stasis. The prescription is Sanren Decoction with modifications (coix seed, cardamom seed, apricot kernel, tongcao, pinellia, tangerine peel, talc, bamboo leaf, thistle, salvia miltiorrhiza, and Imperata root).

(4) Nourishing Yin and reducing fire, cooling blood and harmonizing collaterals: Applicable to the syndrome of Yin deficiency and excess fire. The prescription uses Zhibai Dihuang Pills and Erzhi Pills with modifications (Anemarrhena asphodeloides, Phellodendron chinense, Radix Rehmanniae, Fructus Corni, Dioscorea batatas, Alisma orientalis, Poria, Cortex Moutan, Fructus Ligustri Lucidi, Herba Ecliptae, Rubia cordifolia, Lithospermum officinale, Flos Sophorae, and Paeonia lactiflora).

(5) The method of replenishing qi and nourishing yin, promoting blood circulation and removing blood stasis: It is suitable for the syndrome of qi and yin deficiency with blood stasis. The prescription is modified from Shenqi Dihuang Decoction (Pseudostellariae Radix, Astragalus, Radix Rehmanniae, Fructus Corni, Fructus Ligustri Lucidi, Herba Ecliptae, Rubiae Cordata, Herba Agrimoniae, Cortex Moutan, Paeoniae Rubra, Pheretima, Radix Scutellariae, Lithospermum)

(6) Strengthening the spleen and kidney, promoting blood circulation and removing blood stasis: Applicable to the syndrome of spleen and kidney deficiency with blood stasis. The prescription is Shiquan Dabu Decoction with modifications (astragalus, Codonopsis pilosula, Atractylodes macrocephala, Poria cocos, Coix seed, Rehmannia glutinosa, Viscum album, donkey-hide gelatin beads, Poria cocos, Angelica sinensis, Paeonia lactiflora, Ligusticum chuanxiong, Zedoaria herb, Leonurus japonicus, Achyranthes bidentata).

(7) Nourishing yin and liver, resolving turbidity and eliminating dampness: Applicable to liver and kidney yin deficiency, dampness, turbidity and blood stasis syndrome. The prescription is Qiju Dihuang Wan with modifications (raw rehmannia, wolfberry, glossy privet fruit, chrysanthemum, cornus fruit, peach kernel, ligusticum chuanxiong, pinellia, tangerine peel, magnolia bark, rhubarb).

Prognosis

The overall prognosis is good, and children are better than adults. The prognosis of patients with simple hematuria is very good, while varying degrees of proteinuria and nephrotic syndrome are associated with progressive deterioration of renal function; patients with acute nephritic syndrome and pathological manifestations of grade III or above have a poor prognosis and most of them progress to ESRD.

Prevention

1. In terms of diet, it is advisable to eat more light, nutritious and easily digestible foods. You can often take red dates, longans, lentils, eggplants and other foods. Eat more fresh vegetables and fruits to supplement vitamin C. Avoid spicy and dry foods, fish, shrimp, crabs, smoking and drinking.

2. In terms of medication, avoid using drugs that can reduce platelets, such as cephalosporins, quinine, sodium aminosalate, rifampicin, aspirin, digoxin, quinidine, sulfonamides, promethazine, etc. Avoid using drugs that can inhibit platelet function, such as dipyridamole, dextran, etc.

3. Avoiding allergies is also very important. There are many factors that cause allergies in life, mainly bacterial infections, drugs, food, parasites, etc. If allergic factors such as plants, drugs, foods, microorganisms, etc. have been discovered or suspected, measures such as abstaining from food, avoiding contact and seeking treatment should be taken.