How long can you live with Wilms tumor?

Nephroblastoma is a common malignant tumor. Although it is a tumor with a relatively high incidence rate, the earlier the disease is treated, the better. In life, once the disease is diagnosed, no matter how far it develops, we must persist and not give up. We should go to a regular hospital in time to choose a treatment method that suits us. There is no problem in suppressing the development of the disease. The following is a detailed introduction on how long a person with Nephroblastoma can live?

How long can you live with Wilms tumor?

The 3-year survival rate for patients with nephroblastoma after surgery is approximately 50%, the 5-year survival rate is 40%, and the 10-year survival rate is 20%. Only 3% of patients with nephroblastoma survive surgery and can live for 3 years without any treatment; for patients with stage I nephroblastoma confined to the kidney, the 5-year survival rate is 60-80%; for those with perirenal fat spread (stage II), the 5-year survival rate is 45%; for those with regional lymph node metastasis (stage III), the 5-year survival rate drops to 10-16%; for those with distant metastasis (stage IV), the 5-year survival rate is 8-10%.

How long a patient with Wilms tumor can live depends largely on the treatment plan for Wilms tumor. Since the plan may differ due to individual differences in the condition, how long a patient with Wilms tumor can live involves many issues. Generally speaking, the five-year survival rate of patients after resection of nephroblastoma is between 35% and 40%, and the ten-year survival rate is between 17% and 30%. The prognosis of Wilms tumor is sometimes difficult to estimate. Metastatic lesions may appear 20, 30, or even longer after Wilms tumor resection surgery. How long a patient with advanced Wilms tumor can live is mainly determined by a comprehensive assessment of the primary treatment, auxiliary treatment, patient mood, and patient health. Since advanced Wilms tumor metastasis is more serious, it is crucial for patients to choose the treatment method.

What are the clinical manifestations of Wilms tumor? 1. Abdominal mass. There are no symptoms in the early stages, and abdominal tumors are often the first symptom, accounting for more than 90% of cases, and are often discovered accidentally when bathing the child. Typical symptoms are: weak infants and young children with large lumps in their abdomens, known as "arhat belly". The mass is hard in texture and may have nodules on the surface. There is no obvious tenderness and in the late stage the mass is fixed. 2. Low back pain or abdominal pain. About 1/3 of cases experience pain in the waist or abdomen, which may manifest as local discomfort or even colic, possibly due to bleeding in the tumor. If acute pain is accompanied by fever, abdominal mass, anemia, and hypertension, it is often caused by bleeding under the renal capsule of the tumor. Intra-abdominal rupture of the tumor may present as an acute abdomen. 3. Hematuria. Hematuria occurs in 20% of cases, and in about 10% of cases hematuria is the first symptom noticed and leads to the diagnosis of tumor. It is generally painless and intermittent hematuria, with a small amount, sometimes accompanied by blood clots. However, in most cases, hematuria is a late symptom, and the tumor has grown sufficiently large to infiltrate the renal calyces and enter the renal pelvis. Microscopic examination of urine shows multiple red blood cells in about one-third of cases.

5. Hypertension. It occurs in adult patients and some children, mainly due to compression of renal tissue and excessive secretion of renin.

6. Symptoms of tumor rupture and metastasis. Occasionally, the tumor ruptures spontaneously or after injury, usually preceded by severe pain and acute anemia in the child, and is often diagnosed as a rupture of the liver or spleen. The tumor may rupture in the abdominal cavity or in the flank of the retroperitoneal space. Sometimes the tumor is only a crack with hematoma under the capsule. The tumor mainly metastasizes through the bloodstream, so metastasis to the lungs is most common. After metastasis, there are rarely symptoms such as coughing and hemoptysis, so X-ray lung examination is extremely important. Liver metastases are less common.