Aortic dissection

Aortic dissection

The scientific name for rupture of the aortic dissection is aortic dissection tear. Aortic dissection mainly refers to the tearing of the middle elastic layer of the human aorta under the influence of various factors. After the disease occurs, the patient will feel severe pain, and some serious consequences such as lower limb paresis or paraplegia may also occur. Let’s take a closer look at the situation of aortic dissection.

Introduction The aortic intima is torn, and blood flows into the aortic wall through the tear, causing the middle layer to peel off from the adventitia. Aortic dissection has a high mortality rate. The blood column forms a false lumen in the aortic wall. It usually extends distally from the tear, but less often proximally. Dissection tears occur in the middle muscular layer and can rupture through the adventitia or back to the intima. The false lumen can re-enter the true aortic lumen at any part of the aorta. Dissection tear disrupts the blood supply to the aorta and causes aortic valve insufficiency. Aortic rupture usually into the pericardial space or left pleural space, which can rapidly lead to death. Dissections can originate anywhere in the aorta, but the most common sites are the proximal ascending aorta, within 5 cm of the aortic valve, and below the opening of the left subclavian artery in the thoracic descending aorta. It is rare for dissection to be confined to individual arteries such as the coronary and carotid arteries.

Etiology: In most patients, the smooth muscle and elastic tissue in the middle layer of the aorta undergo degeneration, sometimes with cystic changes (cystic necrosis in the middle layer). The most common complication of medial degeneration is hypertension, which occurs in > 2/3 of cases, and is particularly prevalent with distal dissections. Others include hereditary connective tissue disorders, particularly Marfan and Ehlers-Danlos syndromes; congenital cardiovascular anomalies such as coarctation of the aorta, patent ductus arteriosus, and bicuspid aortic valve; atherosclerosis; trauma; and granulomatous arteritis. Arterial cannulation and cardiovascular surgery can cause iatrogenic dissection. The most widely used classification is the DeBakey anatomical classification: type I arises from the proximal aorta and extends below the brachiocephalic vessels, type II arises from the same point but is limited to the ascending aorta, and type III arises from the descending aorta below the opening of the left subclavian artery. Another anatomical classification classifies involvement of the ascending aorta as type A and involvement of the descending aorta as type B. Many physicians simply classify ascending aortic dissections as proximal and descending aortic dissections as distal. The disease course is divided into acute and chronic if the course is less than 2 weeks and ≥ 2 weeks respectively.

Symptoms and Signs The main symptom is pain, which occurs suddenly and severely in almost all conscious patients. Often described as tearing or peeling. It is most commonly located in the anterior chest area, but pain is also common in the interscapular area, especially when the descending aorta is torn. When the dissection tear extends along the aorta, the pain often migrates from the original torn area. Sometimes symptoms of a dissecting tear are related to an acute occlusion of an artery, such as a stroke, myocardial infarction, or intestinal infarction, which affects the blood supply to the spinal cord and causes paraparesis or limb ischemia. These manifestations mimic arterial embolism. In 2/3 of patients, the main arterial pulsation is weakened or completely absent, and the pulsation may also be strong or weak at times. Two-thirds of patients with proximal dissection have a murmur of aortic regurgitation and may also have peripheral vascular signs of aortic regurgitation. In a small number of patients, acute and severe aortic regurgitation leads to heart failure. Left-sided pleural effusions are common, reflecting periaortic inflammation causing accumulation of serous fluid or leakage of blood into the left pleural space. Neurological complications include paraparesis or paraplegia due to stroke and spinal cord ischemia, and peripheral neuropathy due to sudden occlusion of limb arteries. Blood leakage from the dissection tear into the pericardial cavity may cause cardiac tamponade.

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