What are the effects and functions of total flavonoids?

The element of total flavonoids has many benefits to the human body. It is mainly a natural element found in plants. It can effectively protect the human hematopoietic system and reduce the damage to the hematopoietic tissue. It can enhance the body's immunity and strengthen the body. It can protect human DNA and eliminate free radicals, etc. So let's introduce in detail the effects and functions of total flavonoids.

effect

1. Protective effect on the hematopoietic system

Hematopoietic tissue is a highly radiosensitive tissue. The main target cells of radiation attack are hematopoietic stem cells, granulocyte progenitor cells, and erythroid progenitor cells. The damage of radiation to the hematopoietic system is mainly to inhibit or destroy the proliferation capacity of hematopoietic stem cells and proliferative pool cells.

Radiation often causes bone marrow suppression, microcirculatory disorders, leukopenia, and damage to the hematopoietic microenvironment. Bioactive substances may promote the recovery of the hematopoietic system by regulating the secretion of hematopoietic-related cytokines; at the same time, they increase the body's

The ability to scavenge ROS reduces the damage to blood-removing tissues, thereby achieving an anti-radiation effect.

2. Protective effect on the immune system

The body's immune system is a sensitive system to radiation damage, among which T lymphocytes are the most sensitive. The body's immune function is disturbed due to radiation damage, which is manifested by a decrease in the number of immune active cells, inhibition or disorder of antibody formation, and a cytokine network.

Malregulation. Long-term immune dysfunction makes patients highly sensitive to pathogens such as bacteria and viruses and other factors, aggravating the condition and leading to premature aging and death. Therefore, the treatment of radiation damage to the immune system is a key part of the treatment of radiation sickness.

Many researchers have studied the protective effects of natural medicines against radiation damage to the immune system from the aspects of induction and regulation of cell networks.

3. Eliminate free radicals and have anti-oxidation effects

In radiation damage, the body produces a large number of free radicals, which are atoms or atomic groups containing unpaired electrons. The vast majority of free radicals in living organisms are derived from oxygen molecules and water molecules, including superoxide anions (O2.-), hydroxyl radicals

The drug can reduce and eliminate the damage caused by radiation by removing free radicals (-OH), hydrogen peroxide (H202:), etc.

4. Protect DNA

DNA is an important target molecule of radiation damage, and many radiobiological effects are manifested through DNA damage. DNA is not only a direct target of radiation, but also one of the indirect targets of free radicals generated by radiation, which ultimately causes

DNA breakage, gene mutation, chromosome recombination, cell transformation and cell death, etc. Therefore, reducing the damage of radiation to DNA is one of the important contents of radiation protection research. [1]