Symptoms of pepsin deficiency

The body cannot lack certain elements. When the body lacks certain elements, it means that the body is currently suffering from some problems, which will cause great trouble to the body. The reduction of pepsin will cause people to have digestive problems, and even symptoms such as reduced gastric juice and gastric acid will occur, and many foods cannot be consumed.

Concept Pepsin determination can be used to identify neurotic hypoacidosis, when it is too little or lacking. The former pepsin content is sometimes normal while the latter lacks both hydrochloric acid and pepsin. It is generally believed that gastric hypochlorhydria is caused by severe organic changes in the gastric mucosa, especially for pernicious anemia, acidosis, and absence of pepsin secretion, which are important diagnostic findings. The secretion of pepsin is often reduced in chronic gastritis, chronic gastric dilatation, chronic duodenitis, etc. Generally, diseases with high basal gastric acid secretion, such as diabetes, increase pepsin activity. In 1836, Theodor Schwann discovered an enzyme that can participate in digestion during his research on the digestive process and named it pepsin. Pepsin was also the first enzyme obtained from animals.

The only proteolytic enzyme in the stomach. Its optimum pH value is 1~2. The main site of action of pepsin is the peptide bond composed of the amino groups of aromatic amino acids or acidic amino acids. This enzyme is synthesized by the chief cells of the gastric glands and secreted in the form of zymogen granules. After being activated by hydrochloric acid in gastric juice, it has the ability to digest protein. Medicinal pepsin can be extracted from the stomachs of pigs, cattle and sheep and is used for indigestion.