Platycodon grandiflorum pictures

Platycodon grandiflorus, also known as burden flower, bell flower, and man-of-war, is a perennial woody plant with a stem height of 20 to 120 cm. It is generally hairless, occasionally densely covered with short hairs, has no branches, and rarely has partial branches. All the leaves are whorled, some are whorled or all are symbiotic, sessile or with very short petioles, the leaves are ovate, ovate-elliptical to lanceolate, the leaf blades are ovate or ovate-lanceolate, the flowers are dark blue or dark purple milky white, it can be used as an ornamental plant; its roots can be used as medicine, with the effects of relieving cough and expectorant, promoting lung function, and draining pus, and it is a common medicine in traditional Chinese medicine.

What are the effects of Platycodon grandiflorum pictures?

Producing vaccines with medicinal value

Blood pressure and expectorant effect

After anesthetized dogs took 1 gram/kg of the decoction orally, the secretion of respiratory mucus increased significantly, and the efficacy was comparable to that of ammonium chloride. Another report suggests that its effect is stronger than that of Coptis chinensis and second only to Coptis chinensis. However, when using the phenol red metabolism assay method, its effect is weaker than that of Coptis chinensis. For anesthetized cats, it also has the effect of promoting the metabolism of respiratory mucus. The expectorant effect is mainly caused by the saponins contained therein, which can irritate the gastric mucosa and cause mild nausea and vomiting, thereby indirectly increasing the excretion of bronchitis. According to the comparison of the hemolytic effect, it is believed that the natural Platycodon grandiflorum is more effective than the cultivated one, the unpeeled one is much more effective than the peeled one, the purple flower one is slightly more effective than the white flower one, the one that has been grown for 2 years has the strongest effect, followed by one year, and the one that has been grown for 3 years has the least effect. Compared with Polygonum multiflorum, the hemolytic effect of Citrus grandis is poor.

Other functions of blood

Oral administration of water or ethanol extract of Platycodon grandiflorum to rabbits can lower blood sugar levels. The effect of lowering blood sugar is more obvious in rabbits with diabetes caused by alloxan, and the reduction of liver glycogen can also be restored after taking the medicine. Platycodon saponins can reduce the cholesterol content in the liver of rats and enhance the metabolism of steroids and gallic acid, thus affecting cholesterol metabolism. In vitro tests showed that the soaking agent had an inhibitory effect on flocculent dermatophytes.

Producing vaccines with side effects

Citrus grandiflorus saponin has a hemolytic effect and cannot be used for injection. After oral administration, it is destroyed by hydrolysis in the digestive system and has no hemolytic effect. The minimum lethal dose when injected into the subcutaneous tissue of mice is 770Mg/kg. The median lethal dose of Platycodon grandiflorum decoction was 24g/kg for mice given by oral gavage, and 40/kg of the decoction was administered to rabbits, all 5 rabbits died within 24 hours, and all survived when the dosage was 20/kg. Platycodon grandiflorum saponins have a strong hemolytic effect, and the hemolytic index varies with the origin, growth period, collection time, processing method, etc., ranging from 1:100 to 1:1000. The hemolytic effect of the phloem is 4.4-6.5 times that of the parenchyma, and the hemolytic effect of unpeeled Platycodon grandiflorum is slightly greater than that of peeled Platycodon grandiflorum. Therefore, Platycodon grandiflorum cannot be administered by injection. The minimum lethal dose injected into the subcutaneous tissue of mice is 770Mg/kg. The median lethal dose of crude citrus stem saponin administered orally to mice and rats is 420 mg/kg and 800 mg/kg respectively for humans, and subcutaneous injection is 22.3 mg/kg and 14.1 mg/kg respectively. Large doses of citrus saponins administered intragastrically can reflect the vomiting center's impulses and cause nausea, vomiting, and vomiting.