Thrombocytopenia Subcutaneous hemorrhage

Subcutaneous bleeding due to thrombocytopenia is a typical manifestation of thrombocytopenia. In addition to skin bleeding, there will also be gingival bleeding, gastrointestinal bleeding, and urinary tract bleeding. The causes of thrombocytopenia are different, and the treatment methods are also different. It is best to treat the disease according to the cause, so as to achieve the best effect and solve the problem of subcutaneous bleeding caused by thrombocytopenia.

Causes 1. Decreased platelet production (1) Hereditary conditions such as Fanconi anemia, congenital amegakaryocytic thrombocytopenia and May-Hegglin anomaly. (2) Acquired aplastic anemia, bone marrow infiltration (malignant tumor bone marrow metastasis, leukemia, myelofibrosis, tuberculosis), chemotherapy drugs, radiation, megakaryocytic aplasia, viral infection (measles, mumps), drugs that affect platelet production (such as alcohol), vitamin B12 and folic acid deficiency. 2. Increased platelet destruction caused by non-immune factors, such as thrombotic thrombocytopenic purpura, pregnancy, infection, hemangioma-thrombocytopenia syndrome, snake bites, acute respiratory distress syndrome, severe burns, etc. 3. Increased platelet destruction caused by immune factors: immune thrombocytopenic purpura, HIV infection, cyclical thrombocytopenia, drug-induced thrombocytopenia (heparin, quinine, quinidine, antipyretic analgesics, penicillin, cephalosporin antibiotics, rifampicin, furosemide, carbamazepine, sodium valproate, sulfonylurea hypoglycemic drugs and phenytoin sodium, etc.), and post-transfusion thrombocytopenia. 4. Abnormal platelet distribution, hypersplenism, and hypothermia. 5. Platelet loss bleeding, extracorporeal perfusion, and hemodialysis. 6. Other pseudothrombocytopenia.