Do I need to take medicine for a long time?

As we all know, cerebral infarction is now a very common disease. After suffering from this disease, the brain's blood vessels are blocked, resulting in a lack of blood supply to the brain for a certain period of time, causing damage to the brain nerves, thus affecting the patient's daily life. Nowadays, many drugs and treatment techniques can help patients with cerebral infarction. Do many patients with cerebral infarction need to take long-term medication after the acute phase?

Long-term medication is required. The main purpose of taking medicine is to prevent the recurrence of cerebral infarction and to prevent the patient from becoming disabled or dying due to the recurrence of cerebral infarction.

At present, oral medications mainly include the following aspects. If there are no contraindications, long-term oral treatment should be used:

1. Antiplatelet drugs: mainly aspirin.

2. Lipid-lowering drugs: simvastatin, atorvastatin, etc.

In addition, blood sugar and blood pressure should be strictly controlled.

The above treatments are all derived from relevant disease prevention and treatment guidelines, are recognized worldwide, and are widely used in clinical practice.

Thrombosis and embolism are the basis of cerebral infarction, so the ideal method is to restore normal blood flow to ischemic brain tissue before necrosis occurs. Early reperfusion of brain tissue with cerebral blood flow can reduce the degree of ischemia and limit the damage to nerve cells and their functions. Thrombolytic therapy can be performed using streptokinase and urokinase. Anticoagulants such as heparin and dicoumarol can be used to prevent thrombus extension and the occurrence of new thrombi.

(1) Ultra-early thrombolytic therapy may restore blood perfusion in the infarcted area and reduce neuronal damage . ① Urokinase (UK): alteplase (recombinant tissue-type plasminogen activator) is commonly used for drug thrombolysis; intravenous thrombolysis with streptokinase (SK) is not recommended because it can easily cause bleeding. ② As an emergency treatment for stroke, arterial thrombolysis can be performed under direct DSA vision through super-selective interventional arterial thrombolysis. Arterial thrombolysis with urokinase combined with low-dose intravenous heparin may be beneficial for patients with stroke in the middle cerebral artery distribution who have symptoms 3 to 6/h.

(2) Brain protection therapy can be used before the onset of the ischemic cascade, which can reduce ischemic brain damage by lowering brain metabolism, intervening in the cytotoxic mechanism induced by ischemia. Including free radical scavengers (oxidase dismutase, barbiturates, vitamin E and vitamin C, 21-aminosteroids, etc.), as well as opioid receptor blockers naloxone, voltage-gated calcium channel blockers, excitatory amino acid receptor blockers and magnesium ions.

(3) Anticoagulant therapy can be used in the short term to prevent thrombus expansion, progressive stroke, and reocclusion after thrombolytic therapy. Commonly used drugs include heparin, heparin calcium (low molecular weight heparin) and warfarin. Coagulation time and prothrombin time should be monitored during treatment, and antagonists such as vitamin K and protamine sulfate should be available to deal with possible bleeding complications.

(4) Fibrinolytic therapy inhibits thrombosis by degrading freeze-dried human fibrinogen in the blood and enhancing the activity of the fibrinolytic system. The drugs available include batroxobin, defibrase, ancrodase,

rod) lumbrokinase, etc.