What are the drugs that promote gastric motility?

What are the drugs that promote gastric motility?

Because of work, many people have little time to take care of themselves. They often eat one meal and skip the next, and their diet is very irregular. Some people often overeat, which can easily lead to insufficient gastrointestinal motility and cause problems with the digestive system. The health of the stomach is very important to us. If the stomach motility is insufficient, it can easily lead to disease. What are the medicines that promote gastric motility?

Massage methods to increase gastric motility

Self-massage can adjust gastrointestinal nerve function, relieve subjective symptoms, and improve digestive function. The operation method is as follows: (l) Abdominal massage: The patient lies on his back with his knees bent. Place your palms together on your abdomen, with the navel as the center, and massage the middle and lower abdomen in a clockwise direction for about 5 minutes, until you feel warmth in your abdomen. The force should be light at first and then heavy, then expand the range to massage the entire abdomen for about 2 minutes. (2) Lumbar rubbing method: The patient sits with the waist bent forward. Put the five fingers of both hands together, place the palms close to the waist, and rub them towards the sacrum vigorously. Repeat this for about 1 minute until the skin feels slightly warm. The above two self-massage methods are performed 1 to 2 times a day for 24 consecutive days, and then treated every other day according to the condition until the symptoms disappear.

What are the drugs that promote gastric motility?

In daily life, we often see some people who work in a hurry, and often put their gastrointestinal tract in "dire straits". If you have an irregular diet for a long time, coupled with the negative emotions caused by high pressure, it will easily cause bloating, fullness and other phenomena over time. In fact, the root cause is insufficient gastric motility or gastroduodenal motility disorder. When gastric motility is insufficient, if you want to quickly restore gastric motility, a good way is to take drugs that promote gastric motility. So what are the drugs that promote gastric motility? Most of the more common prokinetic drugs are dopamine receptor antagonists. Dopamine receptor antagonists can promote gastric emptying, increase lower esophageal sphincter pressure, and promote coordinated movement of the antrum and duodenum. Among them, metoclopramide can pass through the blood-brain barrier and occasionally cause extrapyramidal side effects, with a symptom relief rate of 60% to 80%. Cisapride is an HT4 receptor agonist that promotes the motility of the entire digestive tract, has good therapeutic effects, and can improve gastric emptying by up to 80%.

According to research, gastric motility is often inhibited because the dopamine secreted by our body binds to the receptors on the stomach wall. Domperidone can help patients with bloating restore gastric motility by antagonizing these receptors. Just like a carrot in a hole, if domperidone occupies the hole, then the dopamine "carrot" will naturally not be able to bind to the receptor and affect the patient's gastric motility. The experimental results show that through this mechanism, the active ingredient domperidone of Metoclopramide can be quickly absorbed by the human body within 30 minutes, thereby achieving the purpose of promoting gastric motility, relieving bloating and helping gastric emptying. More importantly, metoclopramide and domperidone tablets have no obvious drug interactions, are well tolerated, are not easy to pass through the blood-brain barrier, and are relatively safe to use. Of course, in addition to metoclopramide, there are many generic drugs on the market that also contain domperidone. According to the academic community's test results on the quality of metoclopramide: In terms of drug dissolution, some scholars selected metoclopramide ® and four other drugs with the same active ingredient as domperidone for dissolution experiments, proving that the solubility and efficiency of domperidone, the active ingredient in metoclopramide ®, are good among these drugs. Therefore, among the drugs that promote gastric motility, metoclopramide and domperidone tablets can be considered to be more effective.

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