What medicine should I take for esophagitis?

Liquid food esophagitis is what we often call the reflux of undigested food in the stomach into the esophagus of the human body. These foods contain some stomach acid that will corrode the tissue cells in the esophagus. Therefore, this disease is often accompanied by pain in the throat. At present, mainstream medicine believes that the key to treating this disease is to inhibit the stomach acid in the human body by taking drugs.

1. What medicine should be taken for reflux esophagitis ? Acid suppression therapy. GERD is fundamentally a motility disorder. Preventing the reflux of gastric contents is the key to treatment. However, to date, the efficacy of anti-reflux prokinetic drugs has been unsatisfactory. Acid suppressants can quickly relieve symptoms and cure esophagitis. Therefore, acid suppression therapy is currently the main method for treating reflux esophagitis. Conventional doses of H2-receptor antagonists (H2RA) can significantly inhibit fasting and nocturnal gastric acid secretion and relieve symptoms in most patients, but the healing rate for RE above grade C is poor.

This type of drug has a weak inhibitory effect on postprandial acid secretion and has a rapid drug resistance reaction, so it is only used in patients with grade A/B esophagitis. The powerful acid-suppressing drug PPI can produce significant and lasting acid-suppressing effect, relieve symptoms quickly, and has a high healing rate for esophagitis. It can be used for all patients with reflux esophagitis. Commonly used drugs include omeprazole (40 mg/day), rabeprazole (20 mg/day), esomeprazole (40 mg/day), etc. Patients with reflux esophagitis require a PPI dose twice that of peptic ulcer treatment, with a course of at least 8-12 weeks.

2. What is reflux esophagitis ? Reflux esophagitis refers to the reflux of gastric and (or) duodenal contents into the esophagus. Gastroesophageal reflux can be divided into physiological and pathological types. Physiological gastroesophageal reflux is seen in normal people and has no clinical significance. If reflux occurs more frequently than normal people and the acidic digestive gastric juice as well as pepsin, bile and pancreatic juice cannot be cleared in time, it will cause inflammation, erosion, ulcer and fibrosis of the esophageal mucosa, which is gastroesophageal reflux disease (GERD). The symptoms of reflux esophagitis are easily confused with those of peptic ulcer and can be misdiagnosed.

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