The role and use of naloxone

Naloxone is a morphine receptor antagonist. It is ineffective when taken orally but takes effect quickly when injected. Mainly used for the diagnosis of opioid overdose or opioid addiction. It is also used as a morphine-type compound anesthetic after surgery to eliminate respiratory depression and induce awakening. So, what are the functions and uses of naloxone? Let's have a simple understanding of this issue. I hope the following points will be helpful to everyone!

Naloxone is an opioid kinase antagonist and is also commonly used in clinical medicine. The main functions and uses of naloxone are as follows: first, to rescue acute poisoning by narcotic analgesics, to antagonize the respiratory depression caused by such drugs, and to awaken patients; second, to antagonize the residual effects of narcotic analgesics, for example, newborns caused by the influence of narcotic analgesics in their pregnant mothers can be treated with this product; third, to rescue patients with subacute ethanol poisoning, to keep patients awake and reduce the harm of alcohol to the human body; fourth, intravenous injection of such drugs can induce withdrawal symptoms in patients suspected of being addicted to narcotic analgesics, and has diagnostic value in clinical medicine; fifth, naloxone has the effect of promoting awakening, and can activate the physiological wakefulness system through the effect of choleretics to keep patients awake, and can be used to awaken general anesthesia and resist shock and some comatose patients.

The effects of naloxone are: first, it can be used to rescue acute poisoning of narcotic analgesics; second, it can be used to antagonize the residual effects of narcotic analgesics; third, it can be used in clinical medicine to rescue subacute ethanol poisoning. These are the three most important effects of naloxone. Subsequently, the main uses of naloxone are mainly two points. First, it can be used to antagonize respiratory depression caused by taking narcotic analgesics; secondly, it can make the patient more conscious and is mostly used in clinical medicine to treat unconscious patients.

Usage method Dosage

Because solutions and specifications are different, please read the drug label carefully or follow the doctor's instructions for usage and dosage.

side effect

Some patients experience dry mouth, nausea and retching, anorexia, fatigue or restlessness, increased blood pressure and increased heart rate, most of which can be recovered spontaneously without any treatment. However, there are reports that some patients may develop arrhythmia, pulmonary edema, and even myocardial infarction.

Contraindications

(1) Use with caution in patients with hypertension or poor heart function. (2) Note on medication: Blood pressure should be based on the patient's specific circumstances and condition, with an appropriate dosage and administration rate. Closely monitor the patient's clinical symptom changes, such as breathing, blood pressure, and heart rate, and take effective measures in time. For those addicted to opioids and other narcotic analgesics, withdrawal symptoms will occur immediately after injecting this product, so be careful to control the dosage.