Naloxone intravenous drip for hangover

It is very easy to get drunk or have symptoms of alcohol poisoning after drinking. At present, our main method of sobering up is to use therapeutic drugs. Common therapeutic drugs include Xingnaojing injection and naloxone injection. Naloxone injection is an opioid receptor blocker. In clinical medicine, we often use it to sober up, especially for patients who become comatose and always want to sleep after drinking. The actual effect is better.

So, what is the method of using naloxone intravenous drip for alcohol detoxification?

It is very easy to get drunk or have symptoms of alcohol poisoning after drinking. At present, our main method of sobering up is to use therapeutic drugs. Common therapeutic drugs include Xingnaojing injection and naloxone injection.

Naloxone injection is an opioid receptor blocker. In clinical medicine, we often use it to sober up, especially for patients who become comatose and always want to sleep after drinking. The actual effect is better.

There are two main methods of administration. The first is intravenous drip, which usually involves adding 4 to 6 mg of naloxone to 250 ml of 0.9% saline and dripping it within one hour.

The second condition is to use the static push method, use 1 to 2 mg static push each time, then use it once every 30 minutes, and use it three times.

Dosage of naloxone for hangover

Naloxone hangover cure: 0.8mg~1.2mg for moderate to severe ethanol poisoning, and repeated administration of 0.4mg~0.8mg is required after one hour.

Naloxone is an opioid receptor antagonist that fully exerts its functions of stimulating nerve centers, stimulating breathing, and inhibiting sympathetic nerves by antagonizing endogenous opioid substances endorphins and enkephalins. It can increase the levels of norepinephrine and adrenaline in the blood and increase blood pressure, thereby completely or partially correcting the nerve center inhibitory effect of opioids. At the same time, naloxone can also enhance the contraction force of the heart, improve blood perfusion of tissues, and help protect the ischemic heart.

Naloxone is mainly used to rescue patients from acute poisoning and antagonize residual effects of narcotic analgesics. It is also used to induce awakening from general anesthesia and resist shock or some comatose patients.

Key side effects: Mild drowsiness, dizziness, nausea, vomiting, increased blood pressure and restlessness. Tachycardia, arrhythmia and pulmonary edema are rare. Large usage can cause changes at the individual behavior level. It can also cause laryngeal spasm.