Why do you get small triple positive

Every unit will organize a physical examination for all employees to go to the unit, and at the same time, some diseases in the body can be discovered in time. When people are doing the physical examination, if they are told that they have small triple positive, they will be very worried. The reasons for small triple positive have a lot to do with the body's immune function and infection factors.

Pathogenesis

It is currently believed that the incidence of hepatitis B is closely related to the body's immune status.

Infection with the hepatitis B virus will inevitably cause an immune response in the body, thereby producing different serum immunological markers. It is currently believed that the pathogenesis of hepatitis B is closely related to the body's immune response, especially the cellular immune response in the body, and the body's age characteristics determine the maturity of the body's immune system. The immune system of infants and young children is in a development process, and the ability to clear viruses is poor at this time, so it is easy to become immune-infected and chronic. The immune system of adults is fully developed and it is easy to clear the immune system in a short period of time, thus manifesting as acute hepatitis B. Chronic hepatitis can also occur when the body's immune function is low, immune tolerance is incomplete, and HBV gene mutations escape immune clearance. When the body is in a hypersensitivity reaction, a large number of antigen-antibody complexes are produced and the compensation system is activated, and with the participation of a large number of inflammatory factors, large areas of liver cell necrosis can occur, that is, severe hepatitis occurs. [2-3]

Clinical manifestations

1. Chronic HBV carriers are mostly asymptomatic and are often in the immune tolerance period. Except for the "big three positives" and positive virus tests, other growth indicators and even pathological indicators are normal. Although no drug treatment is required during this period, regular testing and observation are required to detect disease progression in time. Research on carriers has also shown that a small number of carriers have normal liver function, but the disease still progresses. After several years, it can also progress to hepatitis, cirrhosis and even liver cancer. Therefore, regular check-ups are required to detect disease progression in time and intervene in time.

2. Chronic hepatitis B: It can be divided into three types: mild, moderate and severe according to the condition.

Mild : The condition is relatively mild, with recurrent symptoms of fatigue, dizziness, loss of appetite, aversion to oil, yellow urine, discomfort in the liver area, poor sleep, slightly enlarged liver with slight tenderness, and mild splenomegaly. Some cases have no symptoms or signs. Only 1 or 2 liver function indicators were slightly abnormal.

Moderate: Symptoms, signs, and laboratory tests are between mild and severe.

Severe: There are obvious or persistent symptoms of hepatitis, such as fatigue, poor appetite, abdominal distension, yellow urine, loose stools, etc., accompanied by liver disease face, liver palms, spider nevi, splenomegaly, repeated or persistent increase in ALT and/or aspartate aminotransferase (AST), decreased albumin, and significantly increased immunoglobulin G.