Blood storage requirements

Now the country encourages everyone to donate blood for free, and more and more people are responding to the country’s call and donating blood regularly every year. The storage requirements for blood are relatively strict. Because blood is to be injected into the human body, it must be sealed and frozen. Otherwise, it will easily cause rejection and infection, and in severe cases it may endanger people's lives. So, what are the requirements for blood storage?

1 Scope

This standard specifies the storage requirements for blood.

This standard applies to blood storage in general blood stations and medical institutions.

2 Normative references

The following documents are indispensable for the application of this document. For any referenced document with a date, only the version with the date applies to this document. For any un-dated referenced documents, the latest version (including all amendments) shall apply to this document.

WS/T 203 Common terms in transfusion medicine

3 Terms and definitions

For the purposes of this document, the terms and definitions defined in WS/T 203 and listed below apply.

3.1 Storage device: An instrument or device used for storing blood.

3.2 storage period

The maximum storage period of blood suitable for human transfusion under appropriate conditions.

3.3 Quarantine

Unqualified blood, blood awaiting inspection, blood under quality inspection, and blood that is scrapped are separated from qualified blood and stored in specific areas with clear warning labels (computer information and physical objects) to prevent confusion between physical objects, between physical objects and information, and between information and information.

3.4 Closed system

The disposable plastic blood bag system is designed so that the contents are completely isolated from the external environment of the system during separation, packaging and other disposal processes. The sterile catheter connector combines several closed systems into a new system through sterile high-frequency heating, and after checking that the connections are correct, the new system remains a closed system.

3.5 Open system

The closed system is a disposable plastic blood bag system that is opened during blood separation and other treatment processes, exposed to a local Class 100 cleanliness environment, and then sealed.

3.6 Frozen plasma

The blood components are obtained by separating plasma from whole blood by physical methods and freezing it into a solid state within the validity period, or by separating cold precipitated coagulation factors from fresh frozen plasma and freezing the remaining blood components into a solid state, or by plasma after the one-year storage period of fresh frozen plasma expires.

4 Blood storage facilities

4.1 Blood storage area

4.1.1 When blood is stored continuously for ≥ 24 h in the blood storage area, dual power supply or emergency power generation equipment should be provided.

4.1.2 The space in the blood storage area should meet the requirements of cleanliness, hygiene and isolation, and have fire-proof, theft-proof and rodent-proof safety facilities.

4.1.3 The blood storage area should have sufficient lighting sources.

4.1.4 The blood storage area should be divided into an isolation storage area for blood to be tested, an isolation storage area for qualified blood, and an isolation storage area for scrapped blood, with clear and unambiguous markings.

4.1.5 Blood and blood components should be stored in dedicated blood storage equipment.

4.1.6 Blood storage equipment should have a visual temperature display and an audible and visual alarm for over-temperature.

4.1.7 The automatic temperature monitoring and management system for monitoring blood storage equipment should have an audible and visual alarm device for over-temperature and a 24-hour continuous temperature monitoring electronic record.

4.2 Monitoring of blood storage temperature

4.2.1 When blood storage equipment is manually monitored, the temperature should be monitored and recorded at least once every 4 hours.

4.2.2 When blood storage equipment uses an automatic temperature monitoring and management system, the temperature should be recorded manually at least twice a day, with an interval of more than 8 hours between the two records.

4.2.3 Temperature monitoring records of blood storage equipment should be kept for at least one year after the blood is issued to ensure traceability.

5Whole blood and leukocyte-depleted whole blood

5.1 Whole blood

5.1.1 Storage temperature: 2℃~6℃.

5.1.2 Shelf life: The shelf life of whole blood containing ACD-B or CPD blood preservation solution is 21 days; the shelf life of whole blood containing CPDA-1 (containing adenine) blood preservation solution is 35 days. When using other blood preservation fluids, follow the storage period specified in the instructions.

5.2 Leukocyte-depleted whole blood

5.2.1 Storage temperature: 2℃~6℃.

5.2.2 Shelf life: Same as 5.1.2.

5.2.3 Leukocyte-reduced whole blood should be free of leukocytes within 48 hours after blood collection.