What does hyperthyroidism feel like?

Hyperthyroidism is a group of common endocrine diseases caused by excessive secretion of thyroid hormones due to various reasons. The main clinical manifestations are polyphagia, weight loss, phobia, hyperhidrosis, paralysis, irritation, increased nerve and vascular excitability, hyperthyroidism, varying degrees of thyroid enlargement, proptosis, hand tremor, and repair of ankle vascular bruits. And dizziness and nausea and fatigue and well, you don't have symptoms of hyperthyroidism. The guidance recommends that you go to the hospital for a checkup, not just a brain exam.

1. Clinical manifestations of hypermetabolism.

2. Diffuse enlargement of the thyroid gland.

3. Laboratory examination: If serum thyroid stimulating hormone (TSH) is decreased, serum total thyroxine (TT4), total triiodothyronine (TT3), serum free triiodothyronine (FT3) and serum free thyroxine (FT4) may all be increased, the diagnosis of Graves' disease can be established. Positive thyroid stimulating antibodies (TS-Ab) or positive TSH receptor antibodies (TR-Ab) can further confirm that the disease is autoimmune hyperthyroidism (Graves' disease). Because Graves' disease is a type of autoimmune thyroid disease, positive thyroid peroxidase antibodies (TPO-Ab) and positive thyroglobulin antibodies (TG-Ab) may also appear at the same time.

A small number of patients have decreased TSH and normal FT4, but increased serum free triiodothyronine (FT3), and can be diagnosed with T3 hyperthyroidism. Total thyroxine (TT4) and total triiodothyronine (TT3) are less important than FT4 and FT3 in the diagnosis of hyperthyroidism because they are affected by the level of thyroid hormone-binding globulin.

131 Iodine uptake rate: 24h uptake rate increases and the uptake peak occurs earlier.

Clinical manifestations: Hyperthyroidism is a systemic disease, and all systems of the body may have abnormalities. Taking toxic diffuse goiter as an example, the characteristic clinical manifestations can be summarized into three aspects:

① Increased metabolism and high excitement of the sympathetic nerves. Patients often have increased appetite, easy hunger, weight loss, weakness, fear of heat, sweating, moist skin, and may also have fever, diarrhea, irritability, hyperactivity, insomnia, increased heartbeat, and in severe cases, irregular heart rhythm, enlarged heart, and even heart failure.

② The thyroid gland is diffusely and symmetrically enlarged to varying degrees. The degree of enlargement is not necessarily consistent with the condition of the disease. Due to the dilation of blood vessels and accelerated blood flow in the gland, noises may be heard on the enlarged thyroid gland, or vibrations like a cat's panting may be felt.

③ Eye changes: due to overexcitement of the sympathetic nerves, the palpebral fissure may become larger, the eyelids may retract, blinking may be reduced, and the patient may be in a staring state or have a frightened expression. Some patients may have double vision or conjunctival or corneal edema or rupture due to invasion of the eye muscles and restricted eye movement. The patient often has exophthalmos. Severe eye lesions may cause optic disc and/or retinal edema and hemorrhage. Damage to the optic nerve may cause decreased vision or even blindness.

There are also a few patients whose manifestations are not exactly the same as the above. Some older patients have only a few symptoms or signs, or only prominent symptoms of a certain system, such as obvious weight loss or irregular heart rhythm; some patients are weak, fatigued, tired, and apathetic; some show mental disorders; patients who come to the hospital with limb tremors or recurrent limb weakness or paralysis may also be seen. During examination, some patients do not have diffuse enlargement of the thyroid gland, but enlargement of one side or part of one side. A very small number of patients may be accompanied by localized myxedema in the front of the lower leg, thyroid limb disease at the ends of the hands and feet, or male breast hyperplasia, etc.