The efficacy and function of Dudanpi

As the name of peony bark suggests, peony bark is related to peony. The fact is that peony bark is the root bark of peony. Of course, if we want to use it as a medicinal material, we cannot dig out the peony root bark, cut it into small pieces and use it directly. Instead, we need to dry the peony root bark until the moisture disappears and it turns white before using it as medicine. So what are the effects and functions of eating Dudanpi?

The efficacy of peony bark

Clears away heat; promotes blood circulation and relieves blood stasis. It is used for febrile diseases with heat entering the blood; rash; vomiting and bleeding; hot eyes; fever in the late stage of pathogenic bacteria; hot flashes due to yin deficiency and bone steaming; blood stasis and amenorrhea; dysmenorrhea; carbuncle, swelling and sore; pain caused by falls and injuries; rheumatism and heat arthralgia

The role of peony bark

1. Effects on cardiovascular system: Paeonia lactiflora can increase coronary blood flow, reduce cardiac output and lower left ventricular work in anesthetized dogs. It has a significant protective effect on experimental myocardial ischemia, which lasts for a long time and reduces myocardial oxygen consumption.

2. Effects on the central nervous system: Paeonol has an antipyretic effect on fever in mice caused by oral administration of typhoid and paratyphoid vaccines, and reduces the body temperature of normal mice. Oral administration of paeonol can inhibit the writhing reaction and tail tenderness reaction of mice caused by intraperitoneal injection of acetic acid, counteract the hyperactivity of mice caused by caffeine, significantly prolong the sleep time of mice induced by cyclohexylbarbital sodium, and at high doses can cause the righting reflex of mice to disappear. It can significantly counteract the convulsions caused by pentylenetetrazol, strychnine, nicotinic acid and electric shock. The sites of action are the midbrain reticular formation and thalamus.

3. Anti-inflammatory effect: Intragastric administration of paeonol can inhibit the plantar edema of rats caused by dextran, acetic acid or carrageenan, and can inhibit the enhanced capillary permeability of the mouse abdominal cavity or guinea pig skin caused by acetic acid or 5-hydroxytryptamine, and inhibit the occurrence of stress ulcers in mice.

4. Antibacterial effect: In vitro experiments show that the decoction of moutan bark has a strong antibacterial effect on Bacillus subtilis, Escherichia coli, Salmonella typhi, Salmonella paratyphi, Proteus, Pseudomonas aeruginosa, Staphylococcus, hemolytic Streptococcus, Pneumococcus, Vibrio cholerae, etc. The decoction of peony leaves has a significant antibacterial effect on Shigella dysenteriae, Pseudomonas aeruginosa and Staphylococcus aureus, and its active ingredient is gallic acid.

5. Anticoagulant effect: In vitro tests on human platelets showed that both the water extract of Paeonia lactiflora and Paeoniflorin can inhibit the production of thromboxane A2 by platelet arachidonic acid, thereby inhibiting platelet aggregation. This is due to the inhibition of the cyclooxygenase reaction from arachidonic acid to prostate H2. The methanol extract of Paeonia lactiflora has the effect of inhibiting experimental thrombosis caused by endotoxin.