h79n virus symptoms

Influenza virus is a bacterial infectious disease transmitted from poultry and livestock. Once you contract avian influenza, you often experience symptoms such as rapid breathing, persistent high fever, and physical fatigue. In autumn and winter, when the temperature drops, viruses can easily enter the body through the respiratory tract, making it a high-incidence season for avian influenza. H79N is an extremely harmful avian influenza disease. If not treated in time, it may even be life-threatening. So what are the specific symptoms of h79n?

H7N9 avian influenza is a new type of avian influenza that was first discovered in Shanghai and Anhui at the end of March 2013. The H7N9 avian influenza is a new subtype of influenza virus discovered for the first time in the world. It has not yet been included in my country's notifiable infectious disease monitoring and reporting system, and no vaccine has been launched as of early April 2013. People infected with this virus will develop symptoms such as fever in the early stages. As of April 2013, it has not been confirmed whether this type of virus is contagious from person to person. An investigation in April 2013 showed that the H7N9 avian influenza virus genes came from the genetic recombination of wild birds in East Asia and chicken flocks in Shanghai, Zhejiang and Jiangsu, China. As of January 10, 2015, 134 cases have been confirmed nationwide, 37 deaths, and 76 recoveries. The cases are distributed in Beijing, Shanghai, Jiangsu, Zhejiang, Anhui, Shandong, Henan, Taiwan, Fujian, Dongguan, Shanwei and other places.

Clinical manifestations

The diagnosis and treatment plan points out that the incubation period for human infection with H7N9 avian influenza is generally less than 7 days. Patients generally present with flu-like symptoms, such as fever, cough, and little sputum, which may be accompanied by headache, muscle aches, and general discomfort. The condition of critically ill patients progresses rapidly, manifesting as severe pneumonia, with body temperature mostly remaining above 39°C, dyspnea, and coughing up blood and sputum; it can rapidly progress to acute respiratory distress syndrome, mediastinal emphysema, sepsis, shock, impaired consciousness, and acute kidney injury.

(I) General manifestations

Patients generally present with flu-like symptoms, such as fever, cough, and little sputum, which may be accompanied by headache, muscle aches, and general discomfort. The condition of critically ill patients progresses rapidly, manifesting as severe pneumonia, with body temperature mostly remaining above 39°C, dyspnea, and possible hemoptysis. The disease may rapidly progress to acute respiratory distress syndrome, mediastinal emphysema, sepsis, shock, impaired consciousness, and acute kidney injury.

(2) Laboratory examination

1. Routine blood test. The total white blood cell count is generally not high or is decreased. Severe patients often have a decrease in total white blood cell count and lymphocyte count, as well as a decrease in platelets.

2. Blood biochemistry examination. Creatine kinase, lactate dehydrogenase, aspartate aminotransferase, alanine aminotransferase, C-reactive protein, and myoglobin are often elevated.

3. Pathogenic testing.

(1) Nucleic acid testing. H7N9 avian influenza virus nucleic acid was detected by real time PCR (or RT-PCR) in patient respiratory specimens (such as nasopharyngeal secretions, oral rinses, tracheal aspirates or respiratory epithelial cells).

(2) Virus isolation. Isolation of H7N9 avian influenza virus from respiratory specimens of patients.

(iii) Chest imaging examination. Patients with pneumonia have patchy images in their lungs. The lesions in critically ill patients progress rapidly, showing multiple ground-glass shadows and pulmonary consolidation images in both lungs, which may be accompanied by a small amount of pleural effusion. When ARDS occurs, the lesions are widespread.

(IV) Prognosis The prognosis for severe patients infected with H7N9 avian influenza is poor. Factors affecting prognosis may include patient age, underlying diseases, and comorbidities.