Symptoms of granulomatitis

I believe many friends are not familiar with the symptoms of granulomatitis, but you do not understand the symptoms of this disease, which will lead to your inability to treat granulomatitis in time. The main symptoms of granulomatitis are breast lumps and redness and swelling, so when we find this symptom in our daily life, we should pay attention to it and seek timely treatment. Now let us learn about the symptoms of granulomatitis.

Three symptoms to help you identify granulomatous mastitis

When the following breast problems occur, you should be highly alert to granulomatous mastitis:

① Breast lumps, especially those with redness, swelling, abscesses and ulcers in non-lactating women;

②Those with elevated white blood cell count, rapid erythrocyte sedimentation rate or elevated CRP and imaging features;

③ Biopsy suggests characteristic changes of granulomatous mastitis and can rule out breast tuberculosis, inflammatory breast cancer and periductal inflammation.

How to deal with non-lactation mastitis? Hormone treatment + surgical treatment

"The treatment of granulomatous mastitis is not static. After clarifying the principles, the doctor will develop an individualized and refined treatment plan based on the patient's specific situation. We call it classified treatment." The choice of treatment plan should be based on a comprehensive assessment of the condition.

Among them, steroid hormone therapy is the basis and most important part of the treatment of granulomatous mastitis. The patient is first given methylprednisone under the guidance of a doctor and the efficacy is observed for two weeks. If the effect is obvious, the dosage is reduced and taken for another two weeks. If it continues to be effective, the dosage is reduced again and taken for another two weeks. During this period, if the lesion shrinks and stabilizes to about 2 cm, an extended lesion resection can be performed. After the operation, the dosage is slowly reduced until the drug is stopped. During treatment, attention should be paid to controlling diet, paying attention to drug-related adverse reactions and taking corresponding measures. Some patients with acute inflammation of abscess-type granulomatous mastitis have bacterial infection, so a bacterial culture should be done and antibiotics and other anti-infection treatments should be used based on drug sensitivity. For those who are unable to conduct drug sensitivity testing, amoxicillin clinical trial treatment can be chosen. After the inflammation subsides, those with underlying lesions should first receive steroid hormone treatment according to the medication principles for mass-type granulomatous mastitis.

What to do if hormone therapy is not ideal?

Of course, not every patient with granulomatous mastitis will respond ideally to hormone treatment. For patients with granulomatous mastitis who are ineffective or dependent on hormones, immunosuppressant treatments for inflammatory diseases can be used, and long-term treatment with methotrexate, torchwort root, etc. is also effective. Bromocriptine can be added if there is hypersecretinemia. For patients with difficult identification, extensive lesions, and inappropriate surgery, or patients with refractory granulomatous mastitis caused by infection with Corynebacterium, antibiotics such as amoxicillin or triple antimycobacterial drugs can be used for treatment for 6 months to 1 year to cure the disease and avoid total mastectomy, but the choice must be made with caution.

Surgical treatment is to remove the "core lesion"

"For patients who have achieved ideal results with drug treatment, surgical treatment is still recommended, and refractory cases are not impossible to treat with surgery." For refractory cases that "cannot be treated with surgery", there are also effective surgical treatment methods: "For refractory cases with poor drug treatment effects or inability to tolerate drug side effects, surgical treatment can also be adopted. The key point of the operation is to remove the isolated lesions one by one and scrape them away to the surface skin lesions connected to them, which can achieve good results."

Beware! Wrong diet can easily lead to disease recurrence

"Several patients experienced rapid relapse after eating foods such as bamboo shoots, lychees, and beef." In preventing the recurrence of granulomatous mastitis after surgery, in addition to regular check-ups, dietary guidance is also very important.

Avoid eating foods that promote lactation and those that are spicy, greasy, and other foods that can easily cause "heatiness". 2. Regular follow-up examinations (especially within the first year after surgery) after surgery. Physical examinations and imaging examinations can help monitor recurrence. 3. Treatment of postoperative recurrence should follow the medication principles of the initial treatment, including a new cycle of treatment, traditional Chinese medicine treatment or re-surgery.

Treating granulomatous mastitis is a long process. Patients must have confidence and doctors must have patience.