Is membranous nephritis serious?

Every normal person has two kidneys. The working functions of these two kidneys may be the same, but they are indeed indispensable. Although many patients with kidney disease need to undergo a kidney transplant to continue to survive, if there is only one kidney in the body, the human body will become very weak. Nephritis is a more serious type of kidney disease, and it is caused by damage to the renal mucosa. So is membranous nephritis serious?

Membranous nephropathy is one of the most common causes of nephrotic syndrome in adults, especially in middle-aged and elderly men. In my country, the incidence of membranous nephropathy is second only to IgA nephropathy and mesangial proliferative glomerulonephritis, accounting for 9.54% of primary kidney diseases. Most patients with membranous nephropathy present with nephrotic syndrome or asymptomatic proteinuria. Some patients may have microscopic hematuria and hypertension, and a few may have renal insufficiency. A small number of patients with membranous nephropathy may experience spontaneous remission during the course of the disease. Patients with persistent and excessive proteinuria may develop complications such as infection and venous thrombosis during the course of the disease, and some patients eventually develop renal insufficiency. Therefore, actively controlling proteinuria and preventing complications are the key to the treatment of membranous nephropathy.

Membranous nephropathy is divided into primary membranous nephropathy and secondary membranous nephropathy according to the presence or absence of secondary causes. The so-called secondary membranous nephropathy refers to membranous nephropathy with a clear cause, which is caused by autoimmune diseases (such as systemic lupus erythematosus), infections (such as hepatitis B), drugs (such as mercury preparations, gold preparations, penicillamine and non-steroidal anti-inflammatory drugs, etc.) and tumors; while the cause of primary membranous nephropathy is currently unclear. For patients with membranous nephropathy, correctly distinguishing secondary membranous nephropathy and finding its cause are crucial to the treatment of the disease. Treatment that eliminates the cause can not only relieve membranous nephropathy, but also avoid serious consequences caused by further deterioration of the primary disease (especially diseases such as tumors).

Membranous nephropathy is an allergic inflammatory disease characterized by glomerular damage and is a relatively common disease. The main clinical manifestations include proteinuria, hematuria, edema and hypertension. The treatment of membranous nephropathy should focus on blocking the process of renal fibrosis and repairing damaged renal intrinsic cells. Urinalysis, blood routine tests, renal function tests, etc. can help examine nephritis patients and understand the related condition.

After reading the article, I believe everyone has their own understanding. Understanding the causes of the disease and targeted prevention and treatment are the fastest and best ways to get rid of the disease.