Does HMG injection have any effect on ovarian follicles?

Some women have been married for several years but have not been able to get pregnant normally. One of the more common reasons is irregular and abnormal ovulation. It is impossible to get pregnant if the follicles do not reach the basal value. The better method is to use drugs to promote ovulation. So, does HMG injection have any effect on follicles? Medically speaking, egg-stimulating injections are more effective, but side effects are not unavoidable.

Are there any side effects of taking ovulation-stimulating injections?

There are certain side effects of taking ovulation-stimulating injections.

Commonly used ovulation-stimulating injections are HMG and HCG, which can induce follicle maturation and promote ovulation. The main side effects include: possible ovarian hyperstimulation syndrome, manifested as abdominal distension, nausea, vomiting, diarrhea, etc., and may also cause ovarian enlargement, ovarian cyst rupture, multiple pregnancy and miscarriage.

Ovulation-stimulating injections are mainly used for infertile patients with anovulation. It is a double-edged sword and there are certain risks if it is abused. The main side effects of ovulation-stimulating injections are: first, it directly leads to abnormal ovulation, which can easily lead to various pregnancy problems; second, it leads to overstimulation of the ovaries, which can easily lead to twins or multiple births, and the incidence of corresponding pregnancy complications will also increase; third, it can cause women to experience symptoms such as dizziness, fatigue, nausea, rash, lower abdominal pain, and breast swelling and pain. Therefore, ovulation-stimulating injections must be used under the guidance of a doctor.

Side effects of ovulation injections

Accelerate menopause

The number of female follicles is limited. Long-term use of ovulation-stimulating injections to accelerate follicle maturation will speed up the depletion of the more than 40,000 follicles stored during puberty. After the follicles are exhausted, estrogen is no longer secreted and menopause comes early.

Increased risk of cancer

Frequent use of ovulation-stimulating injections will cause the body to maintain a high estrogen level for a long time, which may cause ovarian hyperstimulation syndrome, endocrine disorders, electrolyte imbalance, pelvic effusion and even blood clots, and also increase the risk of breast tumors, ovarian cysts or ovarian tumors.

Cause pregnancy complications

Taking ovulation-stimulating injections is relatively more likely to result in multiple births, and can easily cause pregnancy-induced hypertension, premature birth, and miscarriage. The heart, liver, and kidneys of the pregnant woman will also be overloaded during pregnancy. During delivery, the risk of heavy bleeding, DIC (disseminated intravascular coagulation), heart failure and even shock also increases.

Other adverse reactions

Common adverse reactions to ovulation-stimulating injections include abdominal distension, abdominal pain, dizziness, nausea, appetite and weight gain. In addition, there may be increased menstrual flow, irregular bleeding, and in severe cases, breathing difficulties and shock. If symptoms persist, consult a doctor promptly for diagnosis and treatment.

What are the contraindications of taking ovulation injections?

Unexplained abnormal vaginal bleeding during ovulation induction, uterine fibroids, ovarian cysts or enlargement, adrenal insufficiency, and thyroid insufficiency. It should be used with caution in the following conditions: asthma, heart disease, epilepsy, migraine, renal impairment, pituitary hypertrophy or tumors. It is contraindicated for patients with ovarian insufficiency, polycystic ovary, intracranial lesions, and hypothyroidism and adrenal cortex function.