The daily medication structure of patients with vitiligo is extremely complicated. They cannot recover by simply supplementing some vitamins or taking some drugs that can promote melanin coagulation. Each person's condition is different, the severity is different, and the choice of medication is also different. Patients with vitiligo should pay attention to, in addition to taking some oral medications and supplementing various vitamins and trace elements, they should also supplement some substances containing copper. 1. Medication (1) Oral administration of psoralen and its derivatives such as methoxsalen followed by exposure to ultraviolet light. (2) Long-term use of large doses of vitamins such as B vitamins, vitamin C, and vitamin P. (3) Treatments include drugs containing copper, such as 0.5% copper sulfate solution taken orally. (4) Oral immunomodulatory agent levamisole, intramuscular injection of freeze-dried Bacillus Calmette-Guérin (BCG), oral administration of bovine placenta, etc. (5) Skin irritants are applied topically to cause inflammation of the skin and promote pigmentation. Commonly used ones include 30% psoralea corylifolia tincture, nitrogen mustard alcohol, phenol (pure carbolic acid), 25% to 50% trichloroacetic acid, and blister beetle tincture. This method is only suitable for small skin lesions, and blisters may appear on the lesions after application. (6) Corticosteroids: Local packing treatment with various corticosteroids such as beclomethasone dipropionate ointment, halometasone cream, and triamcinolone urea ointment. 2. Surgery Patients with stable skin lesions and no progression can undergo autologous epidermal transplantation. 3. Depigmentation therapy It is suitable for those with large skin lesions that exceed more than half of the body surface area. 3% to 20% hydroquinone monobenzyl ether cream can be applied externally. 4. Physical therapy Treatment is with narrow-wave ultraviolet light, long-wave ultraviolet light or 308nm excimer laser. Topical medications Creams containing corticosteroids are more effective in reducing pigmentation in small areas of the skin. Can be used in combination with other methods. Hormones can cause skin atrophy and even form stretch marks in specific areas and should be used under the guidance of a doctor. The topical calcineurin inhibitor tacrolimus has achieved good results in the treatment of vitiligo and does not have the side effects of long-term topical hormones, so it is worth trying. |
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