What is gout

Gout is a recurrent inflammatory disease caused by purine anabolism in the joints. It is also common in daily life. It mainly causes hyperuricemia, indirect nephritis and functional disorders of joint deformities. It is mainly caused by primary and secondary symptoms. The main signs are joint pain, which often occurs in minor injuries or overeating.

Some key points that occur after the impact of related diseases. The main treatment is to remove some gout joint systems that affect functional activities. Dietary health care is also very important, including adjusting the dietary structure, prohibiting smoking and drinking, and reducing weight.

Gout is a recurrent inflammatory disease caused by increased purine biosynthesis and metabolism, excessive uric acid production or poor uric acid excretion leading to increased uric acid in the blood, and deposition of urate crystals in the synovium, bursa, cartilage and other tissues of the joints. It is a group of heterogeneous diseases caused by the supersaturation of monosodium urate (MSU) crystals or uric acid in the extracellular fluid, resulting in the deposition of crystals in tissues. This disease is characterized by the presence of birefringent sodium urate monohydrate crystals in joint fluid and tophi. Its clinical features are: characteristic acute arthritis, tophi, and interstitial nephritis caused by hyperuricemia and urate crystals and deposition. In severe cases, joint deformities and dysfunctions may occur, often accompanied by uric acid urinary stones. The causes are divided into two categories: primary and secondary.

Acute onset of joint pain is a typical symptom of acute gout. The disease often occurs after minor injuries, overeating or related diseases, and is particularly prone to occur in the distal joints of the limbs. Typical symptoms occur in the toes (foot gout). Urate stones can also cause renal colic. Chronic gout is characterized by destructive joint changes.

Skin symptoms: In about half of cases, urate is deposited under the skin. These nodules are called gouty nodules or tophi. Gout stones often appear as white or pearly nodules (gout pearls) and occur on free curved skin edges (such as the auricle). Other characteristic symptoms of tophi are white or yellow nodules on the finger (toe) joints. Urate deposits in the skin. Round stones may be visible through thinning skin, and they may rupture. Gout nodules near joints tend to occur in groups or fuse. Tophi occur after an acute attack and are painless. If the skin is broken, a white lime-like substance may be released. Microscopic examination shows a carcinogenic mixture of bundles of needle-like substances, which are identified as sodium urate.

The above is an introduction to gout. The treatment of gout and the prevention and treatment of cardiovascular and cerebrovascular complications are also very important. Dietary health care is also very important, including adjusting the dietary structure, prohibiting smoking and drinking, and reducing weight. Therefore, patients who find gout in daily life must receive timely treatment or examination.