What are the symptoms of pathological jaundice?

When it comes to the most common disease among newborns, jaundice is definitely one of them. Jaundice is divided into three types: physiological jaundice, pathological jaundice, and breast milk jaundice. In addition, neonatal pathological jaundice is extremely harmful to newborns, and can easily lead to heart failure and even chronic diseases such as hepatitis. Therefore, pathological jaundice needs to be prevented and treated in a timely manner. So what are the symptoms of pathological jaundice?

In fact, the cause of pathological jaundice is very complicated. Generally speaking, it will occur within 24 hours after the child is born, and it usually lasts for a long time, and may even cause anemia, vomiting and other phenomena. Below we will give you a detailed introduction to the symptoms of pathological jaundice.

Symptoms of pathological jaundice

Jaundice often appears within 24 hours after birth and lasts for more than 2 weeks, and more than 3 weeks in premature infants; jaundice disappears after birth and reappears and progressively worsens. Severe jaundice may be accompanied by kernicterus. In addition, due to different causes, there are often accompanying symptoms of the primary disease that causes jaundice.

Causes of pathological jaundice

1. Excessive destruction of red blood cells in the body due to certain reasons (congenital metabolic enzyme and red blood cell hereditary defects) as well as physical, chemical, biological and immune factors, resulting in anemia and hemolysis, and excess bilirubin raw materials in the blood, can all cause prehepatic jaundice.

2. Due to stones, liver, gallbladder, pancreatic tumors and other inflammations, the bile duct is obstructed and bile cannot be discharged into the small intestine, which can cause post-hepatic jaundice. 3. Congenital non-hemolytic jaundice: Jaundice caused by Gilbert's disease, Erwin's syndrome and neomycin are all caused by bilirubin binding disorders and bilirubin metabolism defects in hepatocytes.

4. When patients with severe heart disease suffer from heart failure, the liver will be congested and swollen for a long time, and jaundice may occur.

5. Drug-induced damage. People with a history of taking medication, such as chlorpromazine, indomethacin (Indomethacin), phenobarbital, sulfonamides, para-aminosalicylic acid, carbarsine, etc., may develop toxic hepatitis.

The dangers of jaundice

1. There are many causes of jaundice in children. For example, hemolytic disease in children, spherocytosis in children, perinatal diseases in children, etc. can cause hyperbilirubinemia and bilirubin encephalopathy, as well as anemia, hypoxia and hypoxic-ischemic encephalopathy. These diseases and pathological changes can lead to brain damage in the fetus and children, and then lead to cerebral palsy.

2. Bilirubin encephalopathy is caused by hyperbilirubinemia and various pediatric diseases in children. Bilirubin encephalopathy in children caused by a combination of premature birth, infection, hypoxia, acidosis, etc. can cause serious brain damage and is an important cause of cerebellar palsy in children.

3. Whether the various treatment measures for hyperbilirubinemia in children are used in a timely and correct manner may lead to unbalanced control of jaundice, or even aggravate jaundice, leading to the occurrence and aggravation of bilirubin encephalopathy. Therefore, inappropriate treatment of hyperbilirubinemia in children is also a cause of cerebral palsy in children.

I believe that parents already know about the symptoms of neonatal pathological jaundice. Jaundice is indeed one of the most harmful diseases. It can not only easily cause anemia, hypoxia, and even varying degrees of brain damage, but in severe cases it can also lead to cerebral palsy. In short, pathological jaundice requires timely prevention, medical treatment and treatment.