Side effects of Dioscorea bulbifera

Chinese medicine is not without side effects, but the side effects are relatively small. Only correct use of the medicine can minimize its side effects. There are many kinds of Chinese medicines we encounter in our lives, and Coptis chinensis is a very typical one. This kind of Chinese medicine also has side effects. If you use it frequently, you must pay attention to its adverse reactions. So, what are the side effects of Coptis chinensis? Let’s take a look below.

One of the side effects is that it can inhibit food intake. The dry tincture and decoction of xanthophyllum have inhibitory effects on both isolated frog hearts and in situ frog hearts, and also on isolated rabbit intestines. It has an excitatory effect on the uterus of late-pregnant rabbits and guinea pigs, causing tonic and rhythmic contractions. The excitatory effect on the uterus can be cancelled by diphenhydramine. The above-mentioned effects of Dioscorea bulbifera tincture are stronger and faster than those of decoction. The acetone extract of the rhizome of Dioscorea bulbifera injected into the abdominal cavity of rats can inhibit feeding.

Dioscorea bulbifera has certain toxicity to liver and kidney tissues, and it is related to the dosage and time of administration. For example, long-term use of Dioscorea bulbifera has certain toxicity to serum alanine aminotransferase and serum non-protein nitrogen, and it is related to the dosage and time of administration. For example, long-term use of Dioscorea bulbifera has certain effects on serum alanine aminotransferase and serum non-protein nitrogen. The median lethal dose of 200% water decoction is 79.98g/kg for oral administration and 25.49g/kg for intraperitoneal injection. Dioscorea bulbifera has a certain therapeutic effect on animal goiter caused by iodine deficiency. The decoction or alcohol extract has an inhibitory effect on the isolated intestine, but an excitatory effect on the non-pregnant uterus, and also has a hemostatic effect. The water extract has different degrees of inhibitory effect on various pathogenic fungi in vitro. It can directly inhibit the myocardium, and the inhibitory effect of the alcohol extract is stronger than that of the water decoction.

After taking Dioscorea bulbifera preparations at regular doses, dry mouth, loss of appetite, nausea, abdominal pain and other digestive tract reactions may also occur. Overdose can cause burning pain in the mouth, tongue, throat, etc., salivation, nausea, vomiting, abdominal pain and diarrhea, pupil constriction, and jaundice in severe cases. Its direct toxic effect is the result of the drug or its substitute products interfering with cell metabolism when they reach a certain concentration in the liver. The accumulation of a large amount of toxic substances in the body can lead to acute liver poisoning, and finally obvious jaundice, hepatic coma, suffocation, and death from cardiac paralysis.