Best treatment for colitis

When it comes to the disease of colitis, I believe many people are not unfamiliar with it. Because colitis is one of the more common gastrointestinal diseases, the main symptoms are abdominal pain, diarrhea, even bloody stools, constipation, etc., as well as loss of appetite, nausea and other symptoms. In severe cases, it can even be life-threatening. Therefore, colitis needs to be checked and treated in time. So what is the best treatment for colitis?

There are many optimal treatments for colitis. Generally, different conditions have different treatment methods. Therefore, if you find suspected symptoms and manifestations of colitis, it is best to go to a regular hospital for examination and treatment in time. The doctor will find a suitable treatment for you.

The onset of colitis is usually slow, and the severity of the disease varies. The main clinical manifestations are diarrhea, abdominal pain, mucus and bloody stools, tenesmus, and even constipation, inability to defecate for several days; it is often accompanied by weight loss and fatigue, and the symptoms often recur. Abdominal pain is usually dull pain or colic, often located in the left lower abdomen or lower abdomen. Other symptoms include loss of appetite, abdominal distension, nausea, vomiting and liver enlargement; there may be tenderness in the left lower abdomen, and sometimes the spasmodic colon can be felt. Common systemic symptoms include fever, anemia, etc. In a small number of patients, the condition suddenly worsens during the chronic course of the disease or becomes explosive at the first onset, with symptoms such as severe diarrhea, 10 to 30 times a day, and stool containing blood, pus, and mucus. They also have high fever, vomiting, tachycardia, exhaustion, dehydration, electrolyte imbalance, confusion, and even colon perforation. Failure to receive timely treatment may result in death.

Causes:

1. Genetics: According to statistics from foreign literature, 15% to 30% of the immediate family members of patients with ulcerative colitis will develop the disease. In addition, studies on twins have shown that monozygosity is more likely to develop the disease than dizygosity, suggesting that the occurrence of this disease may be related to genetic factors. 2. Infection: The pathological changes and clinical manifestations of this disease are similar to those of some colon infectious diseases, so some people believe that infection is the cause of this disease. Among various factors such as bacteria, fungi and viruses, current research shows that viruses are more likely. 3. Autoimmune reaction: Most scholars believe that this disease is an autoimmune disease. Because this disease is often complicated by autoimmune diseases, adrenal cortex hormones can alleviate the condition. Anti-colonic epithelial cell antibodies can be detected in the serum of some patients. After some patients are infected with intestinal bacteria, they may have an immune response to colon epithelial cell antigens, so it is suspected that the occurrence of colitis may be related to abnormal cellular immunity. 4. Neuropsychiatric factors: Some people believe that mental factors play a certain role in the onset of the disease. Most patients have certain personality traits, and have poor psychological tolerance and adaptability to major events in life, which belongs to the category of psychosomatic disease.

diagnosis:

1. Abdominal pain accompanied by tenesmus, persistent or recurrent diarrhea, and discharge of mucus, pus and blood in the stool, and the patient is not responsive to treatment for specific enteritis. Rule out Crohn's disease, bacillary dysentery, amoebic dysentery, intestinal tuberculosis, colon cancer, etc. 2. Systemic and extraintestinal manifestations. 3. Multiple routine stool examinations and cultures did not reveal any pathogens. 4. X-ray barium enema shows rough and edematous intestinal mucosa, multiple small filling defects, granular or nodular, and coarse and disordered folds. The intestinal wall is serrated. In the later stage, the intestine becomes shorter and stiff, the colon bag disappears, and it becomes lead tube-like. 5. Colonoscopy revealed diffuse congestion, edema, erosion, ulceration and increased fragility of the lesion site. The surface is often covered with purulent secretions and blood. Multiple pseudopolyps, intestinal stenosis, and bridge-shaped mucosa. The colon pouches become shallower or disappear. 6. Biopsy shows inflammation, erosion and ulceration of the mucosa with predominant mononuclear cell infiltration. Cryptitis and crypt abscess may also be seen. At the same time, there is glandular disorder and atrophy. Goblet cells are reduced and Paneth cell metaplasia may be seen.

Best treatment for colitis

By blocking the inflammatory response and regulating the immune function, individualized and comprehensive treatment is given according to the patient's condition. In principle, the symptoms of the disease should be controlled as early as possible, remission should be promoted, treatment should be maintained, recurrence should be prevented, complications should be prevented and the timing of surgical treatment should be grasped.

Principles of treatment

(1) Diet: Get enough rest and avoid fatigue and excessive mental stress. Give less irritating, easy to digest, nutritious food, try to avoid foods containing rough fiber, and temporarily stop eating milk and dairy products. Appropriately replenish fluids and electrolytes, and supplement vitamin B and calcium. Take iron supplements and folic acid to treat anemia. Patients with severe illness, frequent diarrhea, and severe malnutrition can be given a period of gastrointestinal elemental diet or parenteral nutrition. (2) Anti-infective drugs: Salicyloylsulfapyridine is effective in treating various types of colitis and preventing complications. Some cause nausea, vomiting, headache, rash, granulocytopenia, anemia and poor liver function. If it is ineffective or has adverse reactions, metronidazole can be used instead. Neomycin and phthalidazole are also effective. (3) Hormone therapy: Adrenal cortical hormones, hydrocortisone and prednisone can improve the general condition, relieve the course of the disease, reduce the frequency of defecation, alleviate recurrent symptoms and increase appetite. However, the effect is not good for some patients, and it may cause ulcer perforation, bleeding and slow healing. It is now believed that the scope of application is small. It can significantly alleviate symptoms and improve the condition of patients with acute outbreaks or severe early attacks. However, the effect is not satisfactory for long-term recurrent attacks. The corticotropin unit is dissolved in glucose solution and dripped intravenously. After the symptoms improve, it is switched to intramuscular injection. Hydrocortisone can be given intravenously, and the dosage can be gradually reduced after symptoms are relieved. Corticosteroids are better than cortisone in relieving symptoms, but are not as effective as cortisone in maintaining relief. This treatment should not be continued for more than 2 weeks if there is no improvement in symptoms. (4) Immunosuppressants: Azathioprine, once daily, can change the course of the disease and suppress clinical manifestations, but cannot change the underlying disease. It is often used during the quiescent phase to reduce relapses, but it may also cause poisoning, so caution should be exercised. 6-Mercaptopurine (6-MP) combined with hormones can alleviate symptoms. (5) Antidiarrheal drugs: They can reduce the frequency of bowel movements and relieve abdominal pain. Commonly used drugs include compound phenoxylate, codeine, and compound camphor tincture. Antidiarrheal drugs may cause toxic megacolon in acute ulcerative colitis and should be used with caution. Sedatives and antispasmodics may also be given. (6) Retention enema: commonly used for rectal and sigmoid colitis, it can relieve symptoms and promote ulcer healing.

Other treatments

1. Rest: Rest is very beneficial for the disease, especially for patients in the active stage, it is important to emphasize adequate rest and reduce mental and physical burden. As the condition improves, the amount of activity can be gradually increased, but strenuous activity should generally be avoided. 2. Diet and nutrition: During the diarrhea period, you should pay attention to supplementing nutrition and appropriately reduce the fiber content in your diet, such as leeks, celery, garlic shoots, etc. You should eat a low-residue diet to reduce the mechanical damage that high fiber content may cause to the colon mucosa. Regarding the issue of colitis patients drinking milk, it depends on whether the diarrhea worsens after drinking milk, because ulcerative colitis patients may be allergic to cow's milk protein. On the other hand, some patients may suffer from diarrhea after drinking milk due to a lack of lactase in the intestines.

2. Traditional Chinese Medicine

Using acupuncture points to treat colitis: Acupuncture points are located on the pathways where energy flows. This kind of pathway is called "pathway", and the normal name for acupuncture points should be "meridian points". If there is any abnormality in the internal organs, it will be reflected in the pathways of the internal organs where the abnormality is located, and further it will be reflected in the meridian points where the energy is not flowing smoothly. Therefore, by stimulating the acupoints, the flow of energy can be smooth, and the effect of curing diseases and health care can be achieved. This is the purpose of acupoint health care treatment. Acupoint health care therapy is indeed very effective in treating diseases, and recently its effectiveness has gradually been analyzed using scientific methods. The conclusion is: the effectiveness of acupoint therapy is to adjust the autonomic nervous system by stimulating the acupoints to achieve the purpose of strengthening the body. Traditional Chinese medicine believes that if the body's circulatory system is disrupted, one will become ill. This so-called state of energy disorder, in other words, is a state of autonomic nervous system imbalance.

After reading the detailed answer to the question above about what is the best treatment for colitis, I believe that you all have a general understanding of colitis. In addition to going to the hospital in time to cooperate with the doctor to receive necessary treatment for colitis, you must also pay attention to your daily diet. You should appropriately reduce the fiber content in your diet, eat less milk and dairy products, etc., and pay attention to rest. This will help you recover faster. Everyone should pay attention.