Causes of Atherosclerosis

Causes of Atherosclerosis

Speaking of arteriosclerosis, it is definitely not an unfamiliar disease for middle-aged and elderly friends. It is one of the common diseases among middle-aged and elderly people nowadays. Moreover, as people now eat too greasy food, the incidence of arteriosclerosis is gradually increasing. If arteriosclerosis occurs in different parts of the body, it will bring different harms to the human body. For example, cerebral arteriosclerosis, renal artery sclerosis, etc., the harm is more serious.

If arteriosclerosis is not treated in time, it may cause sudden blockage of blood vessels and may lead to the patient's death. Therefore, I hope that middle-aged and elderly friends can understand the causes of arteriosclerosis so as to adjust and prevent it fundamentally.

Causes of arteriosclerosis are as follows:

1. Metabolic disorder: Clinical manifestations are related to high high-density lipoprotein levels, while the ratio is not imbalanced, or it is related to an imbalance in the ratio of apolipoproteins.

2. Related to thrombosis: used for thrombus formation, fibrin accumulation and fibrin dissolution.

3. Changes in blood supply to the arterial wall: Once an artery becomes diseased, capillaries will form and penetrate into the intima. If the pressure changes or the supporting tissue necroses, the blood vessels will rupture, causing small subintimal hemorrhages. The final result can cause fatty degeneration and lead to atherosclerotic plaques.

4. Abnormal load on the distal arterial wall: Since high and low blood pressure are proportional to the degree of arteriosclerosis and histological changes, high-pressure blood flow produces tension mechanical damage to the arterial wall, and at the same time promotes local thrombosis. Ultimately, fatty degeneration deposits promote the formation of atherosclerosis.

5. Genetic factors: A family history of arteriosclerosis obliterans is also a high incidence reason.

6. Infection: Because infection can cause changes in the function of blood vessel wall cells and changes in vascular permeability, the immune complexes formed are deposited in the blood vessel walls. It can be said that the activation of complement further damages the vascular endothelium, all of which can promote thrombosis.

7. Other aspects: For example, obesity, diabetes, vitamin deficiency, and imbalance of trace elements are all sources of arteriosclerosis obliterans.

The above-mentioned causes are all causes of arteriosclerosis. In fact, many patients with arteriosclerosis today suffer from this disease due to their daily living habits. For example, they eat too greasy food, or they lack exercise and have the habit of smoking and drinking, etc. These will cause the blood vessels to gradually harden. It is for this reason that there are more male patients than female patients with this disease.

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