Chloramphenicol eye ointment

Some eye diseases are already very common, and there are many types. Everyone should know that keratitis, trachoma, and conjunctivitis are all common eye diseases. Eye diseases have a great impact on us. The eyes will feel painful, and sometimes redness and swelling will appear, which will affect our normal life. We must be able to get treatment in time. Let's learn about chloramphenicol eye ointment below.

Chloramphenicol eye ointment can effectively treat some eye diseases, such as trachoma, conjunctivitis, and some eye diseases. These diseases can make us feel very uncomfortable, especially as if there is something in the eyes that hurts. Such eye diseases must be treated as soon as possible.

Chloramphenicol eye ointment

Indications

Trachoma, blepharitis, keratitis, conjunctivitis, ophthalmology

Adverse Reactions

May cause eye irritation, allergic reaction, etc.

NotesEdit

It is contraindicated for those who are allergic to this product.

Patients who use this product for a long time should undergo an eye examination in advance and pay close attention to the patient's visual function and symptoms of optic neuritis. If any symptoms appear, the drug should be discontinued. Take vitamin C and B vitamins at the same time.

2. Do not let the bottle mouth touch the eyes when applying to the eyes. Tighten the bottle cap after use and do not let the bottle mouth touch the skin to avoid contamination.

[Use in pregnant and lactating women] Although this product is for local use, chloramphenicol has a serious bone marrow suppressive effect. It may cause serious adverse reactions in newborns and breastfeeding infants after use by pregnant and lactating women. Therefore, pregnant and lactating women should use it with caution.

Pharmacology and toxicology

It has bactericidal effect on the following bacteria: Haemophilus influenzae, Streptococcus pneumoniae and Neisseria meningitidis. It only has an antibacterial effect on the following bacteria: Staphylococcus aureus, Streptococcus pyogenes, Streptococcus viridans, group B hemolytic Streptococcus, Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Salmonella typhi, Salmonella paratyphi, Shigella, Bacteroides fragilis and other anaerobic bacteria. The following bacteria are commonly resistant to chloramphenicol: Pseudomonas aeruginosa, Acinetobacter spp., Enterobacter spp., Serratia marcescens, indole-positive Proteus spp., methicillin-resistant Staphylococci, and Enterococcus spp.

This product is an antibacterial agent. Chloramphenicol is fat-soluble and enters bacterial cells by diffusion, and reversibly binds to the 50S subunit of the bacterial ribosome, which blocks the growth of the peptide chain (possibly due to the inhibition of the action of transpeptidase), thereby inhibiting the formation of peptide chains and preventing protein synthesis.

Pharmacological action

This product is a chloramphenicol antibiotic. It has a broad-spectrum antimicrobial activity in vitro, including aerobic Gram-negative and Gram-positive bacteria, anaerobes, Rickettsia, spirochetes and Chlamydia. It has bactericidal effect on the following bacteria: Haemophilus influenzae, Streptococcus pneumoniae and Neisseria meningitidis. It only has an antibacterial effect on the following bacteria: Staphylococcus aureus, Streptococcus pyogenes, Streptococcus viridans, group B hemolytic Streptococcus, Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Salmonella typhi, Salmonella paratyphi, Shigella, Bacteroides fragilis and other anaerobic bacteria. The following bacteria are commonly resistant to chloramphenicol: Pseudomonas aeruginosa, Acinetobacter spp., Enterobacter spp., Serratia marcescens, indole-positive Proteus spp., methicillin-resistant Staphylococci, and Enterococcus spp. This product is an antibacterial agent. Chloramphenicol is fat-soluble and enters bacterial cells by diffusion, and reversibly binds to the 50S subunit of the bacterial ribosome, which blocks the growth of the peptide chain (possibly due to the inhibition of the action of transpeptidase), thereby inhibiting the formation of peptide chains and preventing protein synthesis.

Everyone should know the effect of chloramphenicol eye ointment in treating eye diseases, but there are some issues that need to be paid attention to during use. If some adverse reactions occur, the drug should be stopped in time. In particular, if eye irritation or allergies occur, they must be dealt with scientifically in a timely manner to avoid some adverse consequences.