What is Propionibacterium acnes

Many people are not clear about what kind of substance Propionibacterium acnes is. In fact, if this happens, it will cause great damage to your skin. Especially for teenagers, the chance of this phenomenon will become greater. It will also cause your skin to be severely blocked, eventually leading to a series of skin problems such as blackheads and acne, which cannot be cured.

Propionibacterium acnes, also known as Propionibacterium acnes and Propionibacterium acnes, is the main bacteria that causes acne. Genomic studies have shown that several of the bacteria's genes are capable of producing enzymes and immunogenic proteins that break down skin tissue.

Propionibacterium acnes is a Gram-positive anaerobic short rod that is intracellular and belongs to the normal flora of the skin, generally residing in the hair follicles and sebaceous glands of the skin. As adolescents mature, keratin plugs appear at the openings of hair follicles and the secretion function of the sebaceous glands increases significantly. Because sebum contains more fatty acids and other ingredients, it is suitable for the growth and reproduction of P. acnes, thus becoming one of the main causes of acne.

The ionization constant of Propionibacterium acnes depends largely on the size of the eighth hydroxyl group in the molecule. The content of Propionibacterium acnes in contaminated feed is generally low and is less toxic to most animals than Propionibacterium acnes. Therefore, it can be ignored during feed testing, and the main analysis should be on the Propionibacterium acnes content.

By replacing the phenylalanine in the Propionibacterium acnes molecule with amino acids such as tryptophan, valine, and lysine, a series of Propionibacterium acnes analogs were obtained, among which the analogs substituted with tyrosine, valine, threonine, and alanine were the most toxic, followed by the analogs substituted with methionine, tryptophan, and glutamate, and the analogs substituted with glutamine and proline were the least toxic. Threonine, hydroxyproline and lysine substituted analogs of Propionibacterium acnes also exist in nature.

Traditional Chinese medicines to which Propionibacterium acnes is moderately sensitive include Scutellaria baicalensis, Folium Isatidis, Flos Lonicerae, Viola yedoensis, and Saxifraga sibiricum.

Traditional Chinese medicines that Propionibacterium acnes is highly sensitive to include Salvia miltiorrhiza, Polygonum cuspidatum, Coptis chinensis, Phellodendron chinense, Vitex foetida, and Cinnamon bark.

The antibiotics that Propionibacterium acnes is sensitive to include erythromycin, cephalosporin antibiotics, clindamycin, etc.

Synthetic antibacterial drugs to which Propionibacterium acnes is sensitive include metronidazole, etc.