How to treat chronic nephritis? Diagnostic criteria for chronic nephritis

As people's living standards improve, many people like to eat and drink too much, which puts too much burden on the organs in the body and causes a series of diseases. So what are the diagnostic criteria for chronic nephritis?

Diagnostic criteria for chronic nephritis:

(1) The onset is slow, the condition is protracted, and the clinical manifestations can be mild or severe, or alternating between mild and severe. As the disease progresses, renal function impairment, anemia, and electrolyte imbalance may occur.

(2) There may be one or more of the following symptoms: edema, hypertension, proteinuria, hematuria, and cystic urine. Clinical manifestations vary, sometimes accompanied by nephrotic syndrome or severe hypertension.

(3) Acute attacks of nephritis may occur during the course of the disease, which are often triggered by infection (such as respiratory tract infection) and have symptoms similar to those of acute nephritis. Some cases can be relieved spontaneously, while others may worsen.

Clinical manifestations: The clinical manifestations of chronic nephritis are diverse and vary greatly among individuals. It can occur at any age, mainly in middle-aged people and more commonly in men. Most cases have a slow and insidious onset. Proteinuria, hematuria, edema, and hypertension are the basic clinical manifestations, and there may be varying degrees of renal impairment. The condition may be mild or severe, and gradually develop into chronic renal failure. Early symptoms may include fatigue, tiredness, back pain, poor appetite, and edema may or may not be present and is generally not serious. Some patients have no obvious clinical symptoms. Blood pressure may be normal or slightly elevated. Kidney function is normal or slightly impaired, and this condition may last from years to decades. In addition to the general manifestations of chronic nephritis mentioned above, some patients also have a persistent moderate or above increase in blood pressure (especially diastolic blood pressure). If blood pressure is not well controlled and renal function deteriorates rapidly, the prognosis will be poor. In addition, some patients have acute attacks due to infection, fatigue, or rapid worsening of their condition after using toxic drugs. Their condition can be relieved to a certain extent after timely removal of the inducement and appropriate treatment, but they may also enter irreversible chronic renal failure.

Examination items: urinalysis, 24-hour urine protein quantification, liver function, kidney function, ions, blood sugar, blood lipids, blood routine, kidney color Doppler ultrasound.

Treatment principles: The treatment of chronic nephritis should be aimed at preventing or delaying the progressive deterioration of renal function, improving or alleviating clinical symptoms, and preventing and treating serious complications, rather than eliminating urine protein and red blood cells. Therefore, it is generally not advisable to give glucocorticoids and cytotoxic drugs, and targeted treatment should be carried out according to the patient's specific situation.