How do you get herpes? Four reasons are the most common

Clinically, the occurrence of herpes is actually related to many reasons. Generally speaking, when people are looking for the cause of herpes, they can analyze it from the following four points.

1. Basal cell liquefaction and basement membrane lesions:

Basal cell liquefaction refers to the cavitation or fragmentation of epidermal basal cells. In severe cases, the basal cell layer disappears and the spinous cells are in direct contact with the dermis. Immune, genetic and drug allergies are often the causes of basal cell liquefaction, which is seen in hereditary epidermolysis macrocarcinoma, systemic lupus erythematosus, dermatomyositis, etc. The causes of basement membrane lesions are autoimmune and genetic. Watery dysentery diseases caused by basement membrane lesions include pemphigoid carcinoma, herpes gestationis, dermatitis herpetiformis, etc.

2. Balloon degeneration and reticular degeneration:

Due to intracellular edema, the volume of epidermal cells increases, forming a balloon shape. The cells swell and rupture, and the adjacent remaining cell membranes connect into multiple reticular septa, finally forming multilocular ulcers, which are more common in viral infectious skin diseases.

3. Herpes virus infection:

HSV infection is common among the population, and humans are the natural host of the herpes virus. The main sources of infection are genital herpes patients and asymptomatic virus carriers. The main route of transmission is sexual contact with people with genital herpes, but asymptomatic carriers with a history of herpes are also sources of infection. In adults, the positive rate of genital herpes virus antibodies is relatively high, generally about 10-70%, which mainly varies with socioeconomic status and sexual life.

4. Balloon degeneration and reticular degeneration:

Due to intracellular edema, the volume of epidermal cells increases, forming a balloon shape. The cells swell and rupture, and the adjacent remaining cell membranes connect into multiple reticular septa, finally forming multilocular ulcers, which are more common in viral infectious skin diseases.