What are the side effects of radiotherapy for lung cancer?

Many friends know that chemotherapy treatment can cause great harm to the patient's body, but they don't know what it is specifically. Chemotherapy can cause bone marrow suppression, myocardial damage, impaired kidney function and other hazards, so patients using chemotherapy need to pay more attention to their diet.

1. Bone marrow suppression . Chemotherapy drugs can cause suppression of bone marrow hematopoietic function. Bone marrow stem cells irradiated after radiotherapy are damaged. When the white blood cell count in the blood drops below 1.5×109/L, the risk of infection is 12%. In the hospital, such patients must be protected and isolated, with a sign saying "No visitors" posted at the door of the ward. They must be irradiated with ultraviolet light twice a day, utensils must be cleaned with disinfectant, and oral antibiotics must be taken to prevent infection. Patients with a white blood cell count of less than 1.5×109/L should be admitted to a laminar flow ward. If the white blood cell count is less than 0.1×109/L, the risk of infection is close to 100%. The relationship between the severity of infection and mortality is not only related to the level of leukopenia, but also determined by the duration. The longer the duration, the higher the incidence of infection. After bone marrow suppression, patients often feel general fatigue and have a poor mental state.

2. Myocardial damage. Some chemotherapy drugs are harmful to the myocardium and require electrocardiographic monitoring. People with heart disease should try not to use them. When using drugs that are toxic to the heart, the cumulative amount of the drugs should be calculated, such as anthracyclines, including doxorubicin (Adriamycin, ADM), epirubicin (E-ADM), pirarubicin (THP), etc. The lifetime cumulative dose of doxorubicin is generally controlled at 550 mg.

3. Damage to liver and kidney function. Some chemotherapy drugs can damage the liver and kidneys. Liver and kidney function must be checked to be normal before chemotherapy. For example, cyclophosphamide (CTX) needs to be activated by the liver; cisplatin (DDP) is harmful to the kidneys. If toxic hepatitis or kidney damage caused by chemotherapy drugs occurs, chemotherapy must be stopped and liver protection treatment must be carried out.

4. Hair loss. Some chemotherapy drugs can cause hair loss.

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